지연성 운동장애의 유병율에 관한 연구
Prevalence of Tardive Dyskinesia

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김용식; 최희정
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서울대학교 의과대학
Seoul J Med 1982;23(1):90-96
The purpose of this study is to determine the
prevalence of tardive dyskinesia CTD) in a chronic
population. The examinations were carried out independently by the senior author (K) and the second
author (C). 110 male puticutsjmcan age 29.58) and
l~H female patients (mean age :J0.3G) in ,1 inpatient
wards of National Mental Hospital in Seoul were
examined for the presence of TD by means of Abnormal
Involuntary Movement Scale CAlMS). The
reexamination was done from 8 to 11 weeks after
first examination. The rcliabilities of the AIMS were
assessed by kappa statistic. Interrater reliubiIities and
test-retest rcliabilities for male subjects were satisfactory.
But those of female subjects were not quite
Among the subjects, the patients with a history of
antipsychotic medication for less than 3 months and
organic conditions including drug or alcohol depend·
ence or mental retardation were excluded when the
prevalence rate were determined and the results were
as follows:
1. When TD was defined those with a rating 3 or
higher for anyone or more than one of seven body
parts, the prevalence rate was 19. 15% in male and
21. 7496 in female by the examiner K and 18.0996
in male 12.1796 in female by the examiner C'nnd
13.8396 in male and !J.S796 in female by the rat ing
of both examiner.
2. When TD was defined as those with a rating 3
or higher for global rating, the prevalence rate
was 15. 9696 in male 18.26% in female by the exam
incr K, 8.5% in male and 10.1396 in female by the
examiner C'and 8. Gl% in male and 7.8396 in female
by both examiner.
Among dyskinetic population, moderate dyskinesia
involved extremities were seen most frequently. There
was no significant relationship between the occurrence
of TD and the duration of antipsychotics
treatment. And there was also no significant relationship
between the severity of global rating and age'
and the amount of antipsychotic medication on the
day of the examination in schizophrenic patients.
However, a significant relationship was found between
the global rating and duration of antipsychotics
treatment in male schizophrenic patients. That is
significantly higher proportion of male patients (p<
0.01) with global rating 100 higher compared to
those with global rating 0 had a history of antipsychotic
med ication for more than two years.
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College of Medicine/School of Medicine (의과대학/대학원)Dept. of Medicine (의학과)The Seoul Journal of MedicineThe Seoul Journal of Medicine Vol. 23 No.1 (1982)
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