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Showing results 1 to 21 of 21

Issue Date	Title / Author(s) / Citation	File
2015-03	An NLRP3 inflammasome–triggered Th2-biased adaptive immune response promotes leishmaniasis Gurung, Prajwal; Karki, Rajendra; Vogel, Peter; Watanabe, Makiko; Bix, Mark; Lamkanfi, Mohamed; Kanneganti, Thirumala-Devi Journal of Clinical Investigation, Vol.125 No.3, pp.1329-1338	DOI
2015-03	Concerted Activation of the AIM2 and NLRP3 Inflammasomes Orchestrates Host Protection against Aspergillus Infection Karki, Rajendra; Man, Si Ming; Malireddi, R. K. Subbarao; Gurung, Prajwal; Vogel, Peter; Lamkanfi, Mohamed; Kanneganti, Thirumala-Devi Cell Host and Microbe, Vol.17 No.3, pp.357-368	DOI
2015-05	The transcription factor IRF1 and guanylate-binding proteins target activation of the AIM2 inflammasome by Francisella infection Man, Si Ming; Karki, Rajendra; Malireddi, R. K. Subbarao; Neale, Geoffrey; Vogel, Peter; Yamamoto, Masahiro; Lamkanfi, Mohamed; Kanneganti, Thirumala-Devi Nature Immunology, Vol.16 No.5, pp.467-475	DOI
2015-07	Critical Role for the DNA Sensor AIM2 in Stem Cell Proliferation and Cancer Man, Si Ming; Zhu, Qifan; Zhu, Liqin; Liu, Zhiping; Karki, Rajendra; Malik, Ankit; Sharma, Deepika; Li, Liyuan; Malireddi, R. K. Subbarao; Gurung, Prajwal; Neale, Geoffrey; Olsen, Scott R.; Carter, Robert A.; McGoldrick, Daniel J.; Wu, Gang; Finkelstein, David; Vogel, Peter; Gilbertson, Richard J.; Kanneganti, Thirumala-Devi Cell, Vol.162 No.1, pp.45-58	DOI
2016-08	ZBP1/DAI is an innate sensor of influenza virus triggering the NLRP3 inflammasome and programmed cell death pathways Kuriakose, Teneema; Man, Si Ming; Malireddi, R. K. Subbarao; Karki, Rajendra; Kesavardhana, Sannula; Place, David E.; Neale, Geoffrey; Vogel, Peter; Kanneganti, Thirumala-Devi Science immunology, Vol.1 No.2, p. aag2045	DOI
2016-10	IL-33 regulates the IgA-microbiota axis to restrain IL-1α–dependent colitis and tumorigenesis Malik, Ankit; Sharma, Deepika; Zhu, Qifan; Karki, Rajendra; Guy, Clifford S.; Vogel, Peter; Kanneganti, Thirumala-Devi Journal of Clinical Investigation, Vol.126 No.12, pp.4469-4481	DOI
2016-12	NLRC3 is an inhibitory sensor of PI3K–mTOR pathways in cancer Karki, Rajendra; Man, Si Ming; Malireddi, R. K. Subbarao; Kesavardhana, Sannula; Zhu, Qifan; Burton, Amanda R.; Sharma, Bhesh Raj; Qi, Xiaopeng; Pelletier, Stephane; Vogel, Peter; Rosenstiel, Philip; Kanneganti, Thirumala-Devi Nature, Vol.540, pp.583-587	DOI
2018-03	Pyrin Inflammasome Regulates Tight Junction Integrity to Restrict Colitis and Tumorigenesis Sharma, Deepika; Malik, Ankit; Guy, Clifford S.; Karki, Rajendra; Vogel, Peter; Kanneganti, Thirumala-Devi Gastroenterology, Vol.154 No.4, pp.948-964.e8	DOI
2018-04	ASK Family Kinases Are Required for Optimal NLRP3 Inflammasome Priming Place, David E.; Samir, Parimal; Karki, Rajendra; Briard, Benoit; Vogel, Peter; Kanneganti, Thirumala-Devi American Journal of Pathology, Vol.188 No.4, pp.1021-1030	DOI
2019-02	Fungal ligands released by innate immune effectors promote inflammasome activation during Aspergillus fumigatus infection Briard, Benoit; Karki, Rajendra; Malireddi, R. K. Subbarao; Bhattacharya, Anannya; Place, David E.; Mavuluri, Jayadev; Peters, Jennifer L.; Vogel, Peter; Yamamoto, Masahiro; Kanneganti, Thirumala-Devi Nature Microbiology, Vol.4 No.2, pp.316-327	DOI
2020-03	Interferon inducible GBPs restrict Burkholderia thailandensis motility induced cell-cell fusion Place, David E.; Briard, Benoit; Samir, Parimal; Karki, Rajendra; Bhattacharya, Anannya; Guy, Clifford S.; Peters, Jennifer L.; Frase, Sharon; Vogel, Peter; Neale, Geoffrey; Yamamoto, Masahiro; Kanneganti, Thirumala-Devi PLoS Pathogens, Vol.16 No.3, p. e1008364	DOI
2020-04	Caspase-6 Is a Key Regulator of Innate Immunity, Inflammasome Activation, and Host Defense Zheng, Min; Karki, Rajendra; Vogel, Peter; Kanneganti, Thirumala-Devi Cell, Vol.181 No.3, pp.674-687.e13	DOI
2020-06	Interferon regulatory factor 1 regulates PANoptosis to prevent colorectal cancer Karki, Rajendra; Sharma, Bhesh Raj; Lee, Ein; Banoth, Balaji; Malireddi, R. K. Subbarao; Samir, Parimal; Tuladhar, Shraddha; Mummareddy, Harisankeerth; Burton, Amanda R.; Vogel, Peter; Kanneganti, Thirumala-Devi JCI insight, Vol.5 No.12, p. e136720	DOI
2020-12	Galactosaminogalactan activates the inflammasome to provide host protection Briard, Benoit; Fontaine, Thierry; Samir, Parimal; Place, David E.; Muszkieta, Laetitia; Malireddi, R. K. Subbarao; Karki, Rajendra; Christgen, Shelbi; Bomme, Perrine; Vogel, Peter; Beau, Remi; Mellado, Emilia; Ibrahim-Granet, Oumaima; Henrissat, Bernard; Kalathur, Ravi C.; Robinson, Cam; Latge, Jean-Paul; Kanneganti, Thirumala-Devi Nature, Vol.588 No.7839, pp.688-692	DOI
2021-01	DDX3X coordinates host defense against influenza virus by activating the NLRP3 inflammasome and type I interferon response Kesavardhana, Sannula; Samir, Parimal; Zheng, Min; Malireddi, R. K. Subbarao; Karki, Rajendra; Sharma, Bhesh Raj; Place, David E.; Briard, Benoit; Vogel, Peter; Kanneganti, Thirumala-Devi Journal of Biological Chemistry, Vol.296, p. 100579	DOI
2021-01	Synergism of TNF-α and IFN-γ Triggers Inflammatory Cell Death, Tissue Damage, and Mortality in SARS-CoV-2 Infection and Cytokine Shock Syndromes Karki, Rajendra; Sharma, Bhesh Raj; Tuladhar, Shraddha; Williams, Evan Peter; Zalduondo, Lillian; Samir, Parimal; Zheng, Min; Sundaram, Balamurugan; Banoth, Balaji; Malireddi, R. K. Subbarao; Schreiner, Patrick; Neale, Geoffrey; Vogel, Peter; Webby, Richard; Jonsson, Colleen Beth; Kanneganti, Thirumala-Devi Cell, Vol.184 No.1, pp.149-168.e17	DOI
2021-07	TLR2 senses the SARS-CoV-2 envelope protein to produce inflammatory cytokines Zheng, Min; Karki, Rajendra; Williams, Evan Peter; Yang, Dong; Fitzpatrick, Elizabeth; Vogel, Peter; Jonsson, Colleen Beth; Kanneganti, Thirumala-Devi Nature Immunology, Vol.22 No.7, pp.829-838	DOI
2021-10	ADAR1 restricts ZBP1-mediated immune response and PANoptosis to promote tumorigenesis Karki, Rajendra; Sundaram, Balamurugan; Sharma, Bhesh Raj; Lee, SangJoon; Malireddi, R. K. Subbarao; Lam Nhat Nguyen; Christgen, Shelbi; Zheng, Min; Wang, Yaqiu; Samir, Parimal; Neale, Geoffrey; Vogel, Peter; Kanneganti, Thirumala-Devi Cell Reports, Vol.37 No.3, p. 109858	DOI
2022-02	The Transcription Factor IRF9 Promotes Colorectal Cancer via Modulating the IL-6/STAT3 Signaling Axis Sharma, Bhesh Raj; Karki, Rajendra; Sundaram, Balamurugan; Wang, Yaqiu; Vogel, Peter; Kanneganti, Thirumala-Devi Cancers, Vol.14 No.4, p. 919	DOI
2022-08	ZBP1-dependent inflammatory cell death, PANoptosis, and cytokine storm disrupt IFN therapeutic efficacy during coronavirus infection Karki, Rajendra; Lee, SangJoon; Mall, Raghvendra; Pandian, Nagakannan; Wang, Yaqiu; Sharma, Bhesh Raj; Malireddi, Rk Subbarao; Yang, Dong; Trifkovic, Sanja; Steele, Jacob A.; Connelly, Jon P.; Vishwanath, Gella; Sasikala, Mitnala; Reddy, Duvvur Nageshwar; Vogel, Peter; Pruett-Miller, Shondra M.; Webby, Richard; Jonsson, Colleen Beth; Kanneganti, Thirumala-Devi Science immunology, Vol.7 No.74, p. eabo6294	DOI
2023-06	NLRP12-PANoptosome activates PANoptosis and pathology in response to heme and PAMPs Sundaram, Balamurugan; Pandian, Nagakannan; Mall, Raghvendra; Wang, Yaqiu; Sarkar, Roman; Kim, Hee Jin; Malireddi, R.K. Subbarao; Karki, Rajendra; Janke, Laura J.; Vogel, Peter; Kanneganti, Thirumala-Devi Cell, Vol.186 No.13, pp.2783-2801.e20	DOI