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Avian Biotechnology: Insights from Germ Cell-mediated Transgenic Systems

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dc.contributor.authorSong, Gwonhwa-
dc.contributor.authorPark, Tae Sub-
dc.contributor.authorKim, Tae Min-
dc.contributor.authorHan, Jae Yong-
dc.date.accessioned2017-01-31T04:37:39Z-
dc.date.available2017-01-31T04:37:39Z-
dc.date.issued2010-
dc.identifier.citationJournal- Poultry Science, vol.47 no.3, pp. 197-207ko_KR
dc.identifier.issn1346-7395-
dc.identifier.urihttps://hdl.handle.net/10371/100290-
dc.description.abstractAves species have become valuable models for numerous experimental and biotechnological purposes due to their unique embryological and physiological traits. This review integrates recent progress and new insights into the molecular and physiological mechanisms of transgenic fowl production. Recent reports have indicated that birds are essential for studying vertebrate development and the conservation of endangered bird species, as well as serving as bioreactor hens. Over the last decade, germ cells and genetic modification have become pivotal components for the production of transgenic animals. Three prerequisites must be met for successfully producing transgenic fowl: the e ective manipulation of various types of avian pluripotent cells without the loss of di erentiation capacity, the manipulation of genes of interest without altering normal gene function, and increasing the e ciency of germ line chimera production. An understanding of the cellular and molecular signals that regulate germ cells as well as the development of a stable gene delivery method will make these species indispensable tools for basic research and biotechnological applications.ko_KR
dc.language.isoenko_KR
dc.publisherJapan Poultry Science Associationko_KR
dc.subjectanimal biomodelko_KR
dc.subjectbioreactorko_KR
dc.subjectgerm cellsko_KR
dc.subjecttransgenic fowlko_KR
dc.titleAvian Biotechnology: Insights from Germ Cell-mediated Transgenic Systemsko_KR
dc.typeArticleko_KR
dc.contributor.AlternativeAuthor송권화-
dc.contributor.AlternativeAuthor박태섭-
dc.contributor.AlternativeAuthor김태민-
dc.contributor.AlternativeAuthor한재용-
dc.identifier.doi10.2141/jpsa.009108-
Appears in Collections:
College of Agriculture and Life Sciences (농업생명과학대학)Dept. of Food and Animal Biotechnology (식품·동물생명공학부)Journal Papers (저널논문_식품·동물생명공학부)
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