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Antifungal substances produced by Lactobacillus plantarum LBP-K10 : Lactobacillus plantarum LBPK10 에서 생성된 항진균 물질
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- Authors
- Advisor
- 강사욱
- Major
- 자연과학대학 생명과학부
- Issue Date
- 2014-02
- Publisher
- 서울대학교 대학원
- Keywords
- Lactobacillus plantarum LBP-K10 ; culture filtrate ; cis-cyclo(LVal- L-Pro) ; cis-cyclo(L-Phe-L-Pro) ; Ganoderma boninense ; Candida albicans
- Description
- 학위논문 (석사)-- 서울대학교 대학원 : 생명과학부, 2014. 2. 강사욱.
- Abstract
- Lactobacillus plantarum LBP-K10 was identified to be the most potent
antifungal strain from Korean traditional fermented vegetables. The culture
filtrate of this strain showed remarkable antifungal activity against Ganoderma
boninense. Five fractions from the culture filtrate were observed to have an
inhibitory effect against G. boninense, and electron ionization and chemical
ionization indicated that these compounds might be cyclic dipeptides. Of the
five active fractions, two fractions showed the most significant anti-
Ganoderma activity, and one of these fractions inhibited the growth of
Candida albicans. These compounds were identified to be cis-cyclo(L-Val-LPro)
and cis-cyclo(L-Phe-L-Pro), as confirmed by X-ray crystallography.
- Language
- English
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