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Synthesis and biomedical applications of multifunctional nanoparticles

Cited 79 time in Web of Science Cited 79 time in Scopus
Authors
Kim, Dokyoon; Shin, Kwangsoo; Kwon, Soon Gu; Hyeon, Taeghwan
Issue Date
2018-12
Citation
Advanced Materials, Vol.30 No.49, p. 1802309
Keywords
bioimagingbiomedical applicationsdrug deliverymultifunctionalitynanomedicinenanoparticlestheranosis
Abstract
The accumulated knowledge of nanoparticle (NP) synthesis for the last 30 years has enabled the development of functional NPs for biomedical applications. Especially, NPs with multifunctional capabilities are gaining popularity as the demand for versatile and efficient NP agents increases. Various combinations of functional materials are integrated to form multicomponent NPs with designed size, structure, and multifunctionality. Their use as diagnostic and/or therapeutic tools is demonstrated, suggesting their application potentials in healthcare and medical practice. Here, the recent achievements in the synthesis and biomedical applications of multifunctional NPs are summarized. Starting with a brief overview regarding the advances in NP synthesis and accompanying progress in nanobiotechnology, various components to construct the multifunctional NP agents, which include polymers and mesoporous, magnetic, catalytic, and semiconducting NPs, are discussed together with their overall integration forms, such as NP assembly, hollow/porous structures, or hybrid/doped systems. Following the explanation of the features that multifunctional NP agents can offer, an outlook and a brief comment regarding the future research directions are provided.
ISSN
0935-9648
URI
http://hdl.handle.net/10371/165883
DOI
https://doi.org/10.1002/adma.201802309
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College of Engineering/Engineering Practice School (공과대학/대학원)Dept. of Chemical and Biological Engineering (화학생물공학부)Journal Papers (저널논문_화학생물공학부)
College of Engineering/Engineering Practice School (공과대학/대학원)Dept. of Chemical and Biological Engineering (화학생물공학부)Chemical Convergence for Energy and Environment (에너지환경 화학융합기술전공)Journal Papers (저널논문_에너지환경 화학융합기술전공)
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