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Development of a T1 contrast agent for magnetic resonance imaging using MnO nanoparticles

Cited 540 time in Web of Science Cited 555 time in Scopus
Authors

Na, Hyon Bin; Lee, Jung Hee; An, Kwangjin; Park, Yong Il; Park, Mihyun; Lee, In Su; Nam, Do-Hyun; Kim, Sung Tae; Kim, Seung-Hoon; Kim, Sang-Wook; Lim, Keun-Ho; Kim, Ki-Soo; Kim, Sun-Ok; Hyeon, Taeghwan

Issue Date
2007-07
Publisher
John Wiley & Sons Ltd.
Citation
Angewandte Chemie - International Edition, Vol.46 No.28, pp.5397-5401
Abstract
Contrasting images: A new T1 contrast agent for magnetic resonance imaging (MRI) based on MnO nanoparticles reveals a bright signal enhancement and fine anatomic structures in the T1-weighted MR image of a mouse brain (see picture; left MRI, right MnO-enhanced MRI (MONEMRI)). Furthermore, MnO nanoparticles conjugated with a tumor-specific antibody were used for selectively imaging breast cancer cells in a metastatic tumor in brain. (Figure Presented). © 2007 Wiley-VCH Verlag GmbH & Co. KGaA.
ISSN
1433-7851
URI
https://hdl.handle.net/10371/165887
DOI
https://doi.org/10.1002/anie.200604775
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  • College of Engineering
  • School of Chemical and Biological Engineering
Research Area Chemistry, Materials Science

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