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Development of a T1 contrast agent for magnetic resonance imaging using MnO nanoparticles

Cited 453 time in Web of Science Cited 476 time in Scopus
Authors
Na, Hyon Bin; Lee, Jung Hee; An, Kwangjin; Park, Yong Il; Park, Mihyun; Lee, In Su; Nam, Do-Hyun; Kim, Sung Tae; Kim, Seung-Hoon; Kim, Sang-Wook; Lim, Keun-Ho; Kim, Ki-Soo; Kim, Sun-Ok; Hyeon, Taeghwan
Issue Date
2007-07
Citation
Angewandte Chemie - International Edition, Vol.46 No.28, pp.5397-5401
Keywords
contrast agentsimaging agents magneticresonance imagingmanganesenanoparticles
Abstract
Contrasting images: A new T1 contrast agent for magnetic resonance imaging (MRI) based on MnO nanoparticles reveals a bright signal enhancement and fine anatomic structures in the T1-weighted MR image of a mouse brain (see picture; left MRI, right MnO-enhanced MRI (MONEMRI)). Furthermore, MnO nanoparticles conjugated with a tumor-specific antibody were used for selectively imaging breast cancer cells in a metastatic tumor in brain. (Figure Presented). © 2007 Wiley-VCH Verlag GmbH & Co. KGaA.
ISSN
1433-7851
URI
https://hdl.handle.net/10371/165887
DOI
https://doi.org/10.1002/anie.200604775
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College of Engineering/Engineering Practice School (공과대학/대학원)Dept. of Chemical and Biological Engineering (화학생물공학부)Journal Papers (저널논문_화학생물공학부)
College of Engineering/Engineering Practice School (공과대학/대학원)Dept. of Chemical and Biological Engineering (화학생물공학부)Chemical Convergence for Energy and Environment (에너지환경 화학융합기술전공)Journal Papers (저널논문_에너지환경 화학융합기술전공)
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