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Magnetic field induced aggregation of nanoparticles for sensitive molecular detection

Cited 31 time in Web of Science Cited 31 time in Scopus
Authors
Jun, Bong-Hyun; Kim, Gunsung; Baek, Jongho; Kang, Homan; Kim, Taeho; Hyeon, Taeghwan; Jeong, Dae Hong; Lee, Yoon-Sik
Issue Date
2011-01
Citation
Physical Chemistry Chemical Physics, Vol.13 No.16, pp.7298-7303
Abstract
A molecular detection method utilizing the magnetically induced aggregation of silver nanoparticle (NP)-embedded silica NPs for SERS activation is described. Here, silver embedded magnetic NPs (Ag-M-dots) composed of a magnetic core and silica shells, on whose surface silver NPs were formed, were used. Because the magnetic field induced aggregated Ag-M-dots exhibit a strong SERS signal compared to the dispersed Ag-M-dots, the system allows for the detection of adsorbed Raman label compound even at the 100 fM level. Adenine was tested as a model biocompound and its Raman spectrum could be observed at concentrations as low as 1 pM. The experimental results were supported by the theoretical calculations.
ISSN
1463-9076
URI
https://hdl.handle.net/10371/166219
DOI
https://doi.org/10.1039/c0cp02055a
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College of Engineering/Engineering Practice School (공과대학/대학원)Dept. of Chemical and Biological Engineering (화학생물공학부)Journal Papers (저널논문_화학생물공학부)
College of Engineering/Engineering Practice School (공과대학/대학원)Dept. of Chemical and Biological Engineering (화학생물공학부)Chemical Convergence for Energy and Environment (에너지환경 화학융합기술전공)Journal Papers (저널논문_에너지환경 화학융합기술전공)
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