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Magnetic field induced aggregation of nanoparticles for sensitive molecular detection
Cited 32 time in
Web of Science
Cited 32 time in Scopus
- Authors
- Issue Date
- 2011-01
- Publisher
- Royal Society of Chemistry
- Citation
- Physical Chemistry Chemical Physics, Vol.13 No.16, pp.7298-7303
- Abstract
- A molecular detection method utilizing the magnetically induced aggregation of silver nanoparticle (NP)-embedded silica NPs for SERS activation is described. Here, silver embedded magnetic NPs (Ag-M-dots) composed of a magnetic core and silica shells, on whose surface silver NPs were formed, were used. Because the magnetic field induced aggregated Ag-M-dots exhibit a strong SERS signal compared to the dispersed Ag-M-dots, the system allows for the detection of adsorbed Raman label compound even at the 100 fM level. Adenine was tested as a model biocompound and its Raman spectrum could be observed at concentrations as low as 1 pM. The experimental results were supported by the theoretical calculations.
- ISSN
- 1463-9076
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