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Multifunctional mesoporous silica nanocomposite nanoparticles for pH controlled drug release and dual modal imaging

Cited 67 time in Web of Science Cited 72 time in Scopus
Authors
Lee, Ji Eun; Lee, Dong Jun; Lee, Nohyun; Kim, Byung Hyo; Choi, Seung Hong; Hyeon, Taeghwan
Issue Date
2011-06
Citation
Journal of Materials Chemistry, Vol.21 No.42, pp.16869-16872
Abstract
Multifunctional nanocomposite nanoparticles for simultaneous fluorescence and magnetic resonance (MR) imaging, and pH-sensitive drug release were fabricated by immobilizing pH responsive hydrazone bonds, magnetite nanoparticles and fluorescent dyes in mesoporous silica nanoparticles. pH dependent release of doxorubicin was demonstrated and the nanocomposite nanoparticles show fluorescence emission and MR contrast effect.
ISSN
0959-9428
URI
http://hdl.handle.net/10371/166221
DOI
https://doi.org/10.1039/c1jm11869b
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College of Engineering/Engineering Practice School (공과대학/대학원)Dept. of Chemical and Biological Engineering (화학생물공학부)Journal Papers (저널논문_화학생물공학부)
College of Engineering/Engineering Practice School (공과대학/대학원)Dept. of Chemical and Biological Engineering (화학생물공학부)Chemical Convergence for Energy and Environment (에너지환경 화학융합기술전공)Journal Papers (저널논문_에너지환경 화학융합기술전공)
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