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Multiple-Interaction Ligands Inspired by Mussel Adhesive Protein: Synthesis of Highly Stable and Biocompatible Nanoparticles

Cited 111 time in Web of Science Cited 114 time in Scopus
Authors

Ling, Daishun; Park, Wooram; Park, Yong Il; Lee, Nohyun; Li, Fangyuan; Song, Changyeong; Yang, Su-Geun; Choi, Seung Hong; Na, Kun; Hyeon, Taeghwan

Issue Date
2011-11
Publisher
John Wiley & Sons Ltd.
Citation
Angewandte Chemie - International Edition, Vol.50 No.48, pp.11360-11365
Abstract
All bound up: A poly(L-3,4-dihydroxyphenylalanine)-based ligand converts hydrophobic nanoparticles into hydrophilic and biocompatible species through several binding modes. Nanoparticles functionalized with this ligand (see picture) are highly stable in various aqueous solutions. A successful invivo MRI application using functionalized Fe 3O 4 nanoparticles confirmed their suitability for various biomedical applications.
ISSN
1433-7851
URI
https://hdl.handle.net/10371/166224
DOI
https://doi.org/10.1002/anie.201101521
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  • College of Engineering
  • School of Chemical and Biological Engineering
Research Area Chemistry, Materials Science

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