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Multifunctional capsule-in-capsules for immunoprotection and trimodal imaging
Cited 75 time in
Web of Science
Cited 74 time in Scopus
- Authors
- Issue Date
- 2011
- Publisher
- John Wiley & Sons Ltd.
- Citation
- Angewandte Chemie - International Edition, Vol.50 No.10, pp.2317-2321
- Abstract
- (Figure Presented) The separate encapsulation of nanoparticles (NPs) and pancreatic islets in an alginate capsule-in-capsule (CIC) structure prevents the nanoparticles being toxic to the cells while housing a high payload of nanoparticles for imaging purposes (see picture). The CIC-encapsulated islets showed an improved insulin secretion over cells encapsulated in single capsules and their transplantation into diabetic mice restored normal glycemia. © 2011 Wiley-VCH Verlag GmbH & Co. KGaA.
- ISSN
- 1433-7851
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