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Graphene- Regulated Cardiomyogenic Differentiation Process of Mesenchymal Stem Cells by Enhancing the Expression of Extracellular Matrix Proteins and Cell Signaling Molecules

Cited 99 time in Web of Science Cited 99 time in Scopus
Authors
Park, Jooyeon; Park, Subeom; Ryu, Seungmi; Bhang, Suk Ho; Kim, Jangho; Yoon, Jeong-Kee; Park, Yoon Hwan; Cho, Sung-Pyo; Lee, Seahyoung; Hong, Byung Hee; Kim, Byung-Soo
Issue Date
2014-02
Citation
Advanced healthcare materials, Vol.3 No.2, pp.176-181
Keywords
cardiomyogeniccell differentiationextracellular matrixgraphenemesenchymal stem cells
Abstract
The potential of graphene as a mesenchymal stem cell (MSC) culture substrate to promote cardiomyogenic differentiation is demonstrated. Graphene exhibits no sign of cytotoxicity for stem cell culture. MSCs are committed toward cardiomyogenic lineage by simply culturing them on graphene. This may be attributed, at least partially, to the regulation of expression levels of extracellular matrix and signaling molecules.
ISSN
2192-2640
URI
https://hdl.handle.net/10371/172146
DOI
https://doi.org/10.1002/adhm.201300177
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College of Natural Sciences (자연과학대학)Dept. of Chemistry (화학부)Journal Papers (저널논문_화학부)
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