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Biodegradable Nano-Polymeric System for Efficient Akt1 siRNA Delivery
Cited 19 time in
Web of Science
Cited 19 time in Scopus
- Authors
- Issue Date
- 2010-05
- Publisher
- American Scientific Publishers
- Citation
- Journal of Nanoscience and Nanotechnology, Vol.10 No.5, pp.3366-3369
- Abstract
- Biodegradable nano-polymeric carrier composed of polycaprolactone (PCL) and polyethylenimine (PEI) (BNPP) was successfully synthesized for the delivery of sh/siRNA in lung cancer cells. BNPP efficiently and safely delivered siRNA in lung cancer cells. BNPP-delivered Akt1 siRNA silenced Akt1 protein, and reduced the cancer cell survival, proliferation, malignancy and metastasis.
- ISSN
- 1533-4880
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- There are no files associated with this item.
Related Researcher
- Cho, Myung Haing조명행
- Professor
- College of Veterinary Medicine
- Department of Veterinary Medicine
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