S-Space College of Veterinary Medicine (수의과대학) Dept. of Veterinary Medicine (수의학과) Journal Papers (저널논문_수의학과)
Surface-enhanced Raman scattering-active nanostructures and strategies for bioassays
- Jun, Bong-Hyun; Kim, Gunsung; Noh, Mi Suk; Kang, Homan; Kim, Yong-Kweon; Cho, Myung-Haing; Jeong, Dae Hong; Lee, Yoon-Sik
- Issue Date
- Nanomedicine, Vol.6 No.8, pp.1463-1480
- bioassay; bioimaging; encoding; nanomaterials; SERS; SERS-based strategy; SERS material; surface-enhanced Raman scattering; tagging
- Surface-enhanced Raman scattering (SERS) techniques offer a number of advantages in molecular detection and ana-lysis, particularly in terms of the multiplex detection of biomolecules. So far, many new SERS-based substrates and analytical techniques have been reported. For easy understanding, various SERS techniques are classified into the following four categories: adsorption-mediated direct detection; antibody-or ligand-mediated direct detection; binding catalyzed indirect detection; and tag-based indirect detection. Among these, recent successes of SERS tagging/encoding (nano/micro) materials and detection methods are highlighted, including our recent works. Some novel SERS-based strategies for the detection of several biological molecules are also introduced.
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