Publications
Detailed Information
Porcine OCT4 reporter system as a tool for monitoring pluripotency states
Cited 0 time in
Web of Science
Cited 0 time in Scopus
- Authors
- Issue Date
- 2021-12
- Publisher
- 사단법인 한국동물생명공학회
- Citation
- Journal of Animal Reproduciton and Biotechnology, Vol.36 No.4, pp.175-182
- Abstract
- Pluripotent stem cells could self-renew and differentiate into various cells. In particular, porcine pluripotent stem cells are useful for preclinical therapy, transgenic animals, and agricultural usage. These stem cells have naïve and primed pluripotent states. Naïve pluripotent stem cells represented by mouse embryonic stem cells form chimeras after blastocyst injection. Primed pluripotent stem cells represented by mouse epiblast stem cells and human embryonic stem cells. They could not produce chimeras after blastocyst injection. Populations of embryonic stem cells are not homogenous; therefore, reporter systems are used to clarify the status of stem cells and to isolate the cells. For this reason, studies of the OCT4 reporter system have been conducted for decades. This review will discuss the naïve and primed pluripotent states and recent progress in the development of porcine OCT4 reporter systems.
- ISSN
- 2671-4639
- Files in This Item:
- There are no files associated with this item.
Item View & Download Count
Items in S-Space are protected by copyright, with all rights reserved, unless otherwise indicated.