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Voyage to minimal base editors

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Authors

Song, Beomjong; Bae, Sangsu

Issue Date
2022-09
Publisher
Nature Publishing Group
Citation
Nature Chemical Biology, Vol.18 No.9, pp.920-921
Abstract
Transposon-associated transposase B (TnpB) is the putative ancestor of Cas nucleases. A TnpB-based adenine base editor has now been developed that is small enough to be loaded into a single AAV vector without compromising editing activity.
ISSN
1552-4450
URI
https://hdl.handle.net/10371/187195
DOI
https://doi.org/10.1038/s41589-022-01101-8
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