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Local Drug Delivery Strategies for Glioblastoma Treatment
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Cha, Gi Doo | - |
dc.contributor.author | Jung, Sonwoo | - |
dc.contributor.author | Choi, Seung Hong | - |
dc.contributor.author | Kim, Dae Hyeong | - |
dc.date.accessioned | 2023-03-20T08:38:43Z | - |
dc.date.available | 2023-03-20T08:38:43Z | - |
dc.date.created | 2022-09-06 | - |
dc.date.issued | 2022-07 | - |
dc.identifier.citation | Brain Tumor Research and Treatment, Vol.10 No.3, pp.151-157 | - |
dc.identifier.issn | 2288-2405 | - |
dc.identifier.uri | https://hdl.handle.net/10371/189435 | - |
dc.description.abstract | Glioblastoma multiforme (GBM) is a brain tumor notorious for its malignancy. The key reason for the lim- ited efficacy of standard treatment is the high recurrence rate of GBM, even after surgical resection. Hence, intensive postsurgical chemical therapies, such as the systemic delivery of various drugs and/ or drug combinations, are typically followed after surgery. However, overcoming the blood-brain barrier by systemic administration to efficiently deliver drugs to the brain tumor remains a daunting goal. There- fore, various local drug delivery methods showing potential for improved therapeutic efficacy have been proposed. In particular, the recent application of electronic devices for the controlled delivery of che- motherapy drugs to GBM tissue has attracted attention. We herein review the recent progress of local drug delivery strategies, including electronics-assisted strategies, at the research and commercial level. We also present a brief discussion of the unsolved challenges and future research direction of localized chemotherapy methods for GBM. | - |
dc.language | 영어 | - |
dc.publisher | 대한뇌종양학회 | - |
dc.title | Local Drug Delivery Strategies for Glioblastoma Treatment | - |
dc.type | Article | - |
dc.citation.journaltitle | Brain Tumor Research and Treatment | - |
dc.citation.endpage | 157 | - |
dc.citation.number | 3 | - |
dc.citation.startpage | 151 | - |
dc.citation.volume | 10 | - |
dc.identifier.kciid | ART002863747 | - |
dc.description.isOpenAccess | N | - |
dc.contributor.affiliatedAuthor | Choi, Seung Hong | - |
dc.contributor.affiliatedAuthor | Kim, Dae Hyeong | - |
dc.description.journalClass | 2 | - |
dc.subject.keywordAuthor | Drug administration routes | - |
dc.subject.keywordAuthor | Chemotherapy | - |
dc.subject.keywordAuthor | Blood-brain barrier | - |
dc.subject.keywordAuthor | Brain tumor | - |
dc.subject.keywordAuthor | Absorbable implants | - |
dc.subject.keywordAuthor | Drug delivery systems. | - |
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