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Polydiacetylenyl beta-cyclodextrin based smart vesicles for colorimetric assay of arginine and lysine
DC Field | Value | Language |
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dc.contributor.author | Cho, Eunae | - |
dc.contributor.author | Kim, Hwanhee | - |
dc.contributor.author | Choi, Youngjin | - |
dc.contributor.author | Paik, Seung R. | - |
dc.contributor.author | Jung, Seunho | - |
dc.date.accessioned | 2023-04-19T08:40:01Z | - |
dc.date.available | 2023-04-19T08:40:01Z | - |
dc.date.created | 2018-04-17 | - |
dc.date.issued | 2016-08 | - |
dc.identifier.citation | Scientific Reports, Vol.6, p. 31115 | - |
dc.identifier.issn | 2045-2322 | - |
dc.identifier.uri | https://hdl.handle.net/10371/191095 | - |
dc.description.abstract | Selective visualization of arginine and lysine has been explored among 20 amino acids using the hybrid conjugate of beta-cyclodextrin (beta-CD) and polydiacetylene (PDA). The mono pentacosa-10,12-diynyl aminomethyl group was successfully coupled to either the primary or the secondary face of beta-CD, where mono-6-amino-6-deoxy-beta-CD or mono-3-amino-3-deoxy-beta-CD reacted with the N-hydroxysuccinimide ester of 10,12-pentacosadiynoic acid. In this combinatorial system, the cylindrical beta-cyclodextrin functions as a channel for the introduction of the cationic amino acids to the artificial membrane. The membrane perturbation and aggregation by the target amino acids could be exclusively visualized as a blue to red color change based on the responsive polydiacetylene domain. These interesting findings demonstrated that the developed beta-CD conjugated PDA system may offer a new method of cell-penetrating mechanism, a promising vector system, as well as impact the production industry of arginine or lysine. | - |
dc.language | 영어 | - |
dc.publisher | Nature Publishing Group | - |
dc.title | Polydiacetylenyl beta-cyclodextrin based smart vesicles for colorimetric assay of arginine and lysine | - |
dc.type | Article | - |
dc.identifier.doi | 10.1038/srep31115 | - |
dc.citation.journaltitle | Scientific Reports | - |
dc.identifier.wosid | 000381028100001 | - |
dc.identifier.scopusid | 2-s2.0-84981156246 | - |
dc.citation.startpage | 31115 | - |
dc.citation.volume | 6 | - |
dc.description.isOpenAccess | Y | - |
dc.contributor.affiliatedAuthor | Paik, Seung R. | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.subject.keywordPlus | CORYNEBACTERIUM-GLUTAMICUM | - |
dc.subject.keywordPlus | INCLUSION COMPLEXES | - |
dc.subject.keywordPlus | AMINO-ACIDS | - |
dc.subject.keywordPlus | LABEL-FREE | - |
dc.subject.keywordPlus | PEPTIDES | - |
dc.subject.keywordPlus | NANOPARTICLES | - |
dc.subject.keywordPlus | AGGREGATION | - |
dc.subject.keywordPlus | MECHANISMS | - |
dc.subject.keywordPlus | BIOSENSOR | - |
dc.subject.keywordPlus | POLYMER | - |
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