Publications
Detailed Information
Comparative study of the ocular irritation potential of various alkyl polyglucoside surfactants
Cited 4 time in
Web of Science
Cited 5 time in Scopus
- Authors
- Issue Date
- 2010-03
- Publisher
- Taylor & Francis
- Citation
- Cutaneous and Ocular Toxicology, Vol.29 No.1, pp.50-56
- Abstract
- In the present work, we assessed the relationship between alkyl carbon chain length and ocular irritation potentials using the hen's egg test-chorioallantoic membrane (HET-CAM) and bovine corneal opacity and permeability (BCOP) assays using 5 commercial alkyl polyglucoside surfactants with different compositions of alkyl chain lengths (C6-C16). With HET-CAM, there was a good correlation between the proportion of C(10) alkyl polyglucoside and the eye irritation potential Q score (r(2) = 0.912, p = .011). There were no significant differences between the proportion of C(10) alkyl polyglucoside and corneal opacity in BCOP assays; however, there was a relatively high positive correlation between the proportion of C(10) alkyl carbon chain lengths and corneal permeability (r(2) = 0.736, p = .063)..
- ISSN
- 1556-9527
- Files in This Item:
- There are no files associated with this item.
- Appears in Collections:
Item View & Download Count
Items in S-Space are protected by copyright, with all rights reserved, unless otherwise indicated.