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Cholesterol lowering effect of SG-GN3, the extract of salted and fermented small shrimps, Acetes japonicus, in Triton WR-1339 or high cholesterol-diet induced hypercholesterolemic rats
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Cited 9 time in Scopus
- Authors
- Issue Date
- 2004-04
- Publisher
- Elsevier BV
- Citation
- Journal of Ethnopharmacology, Vol.91 No.2-3, pp.231-235
- Abstract
- The cholesterol lowering effect of SG-GN3, the extract of salted and fermented small shrimps, Acetes japonicus, was investigated in hypercholesterolemic animal models. Hypercholesterolemia was induced with Triton WR-1339 (nonionic detergent) or high cholesterol (HC)-diet. SG-GN3 significantly decreased total cholesterol (TC) induced Triton WR-1339 model at 30 post-treatment hour (549.80 +/- 152.46 mg/dl) compared to the control which induced by only Triton WR-1339 (798.84 +/- 94.98 mg/dl), whereas high-density lipoprotein (HDL) content did not decrease (P < 0.05). In HC-diet model, TC content significantly decreased by SG-GN3 treatment at 3 post-treatment day (P < 0.05). These results Suggest that SG-GN3 effectively decreased serum TC level in hypercholesterolemic animal models. (C) 2004 Elsevier Ireland Ltd. All rights reserved.
- ISSN
- 0378-8741
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