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Virus isolation from the first patient with SARS-CoV-2 in Korea
Cited 154 time in
Web of Science
Cited 166 time in Scopus
- Authors
- Issue Date
- 2020-02
- Publisher
- 대한의학회
- Citation
- Journal of Korean Medical Science, Vol.35 No.7, p. e84
- Abstract
- Novel coronavirus (SARS-CoV-2) is found to cause a large outbreak started from Wuhan since December 2019 in China and SARS-CoV-2 infections have been reported with epidemiological linkage to China in 25 countries until now. We isolated SARS-CoV-2 from the oropharyngeal sample obtained from the patient with the first laboratory-confirmed SARSCoV-2 infection in Korea. Cytopathic effects of SARS-CoV-2 in the Vero cell cultures were confluent 3 days after the first blind passage of the sample. Coronavirus was confirmed with spherical particle having a fringe reminiscent of crown on transmission electron microscopy. Phylogenetic analyses of whole genome sequences showed that it clustered with other SARS-CoV-2 reported from Wuhan.
- ISSN
- 1011-8934
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