Publications

Detailed Information

Trans-differentiation via epigenetics: A new paradigm in the bone regeneration

Cited 0 time in Web of Science Cited 0 time in Scopus
Authors

Cho, Young-Dan; Ryoo, Hyun Mo

Issue Date
2018-04
Publisher
대한골대사학회
Citation
대한골대사학회지, Vol.25 No.1, pp.9-13
Abstract
In regenerative medicine, growing cells or tissues in the laboratory is necessary when damaged cells can not heal by themselves. Acquisition of the required cells from the patients own cells or tissues is an ideal option without additive side effects. In this context, cell reprogramming methods, including the use of induced pluripotent stem cells (iPSCs) and trans-differentiation, have been widely studied in regenerative research. Both approaches have advantages and disadvantages, and the possibility of de-differentiation because of the epigenetic memory of iPSCs has strengthened the need for controlling the epigenetic background for successful cell reprogramming. Therefore, interest in epigenetics has increased in the field of regenerative medicine. Herein, we outline in detail the cell trans-differentiation method using epigenetic modification for bone regeneration in comparison to the use of iPSCs.
ISSN
2287-6375
URI
https://hdl.handle.net/10371/200570
DOI
https://doi.org/10.11005/jbm.2018.25.1.9
Files in This Item:
There are no files associated with this item.
Appears in Collections:

Related Researcher

Cho, Young-Dan Image

Cho, Young-Dan조영단
(기금)조교수
  • School of Dentistry
  • Department of Dentistry
Research Area Alveolar bone regeneration, Dental implant surface modification, Periomics

Altmetrics

Item View & Download Count

  • mendeley

Items in S-Space are protected by copyright, with all rights reserved, unless otherwise indicated.

Share