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Isolation of a new Orientia tsutsugamushi serotype

Cited 11 time in Web of Science Cited 12 time in Scopus
Authors

Seong, SY; Park, SG; Kim, HR; Han, TH; Kang, JS; Choi, MS; Kim, IS; Chang, WH

Issue Date
1997-06
Publisher
Center for Academic Publications Japan
Citation
Microbiology and Immunology, Vol.41 No.6, pp.437-443
Abstract
Orientia tsutsugamushi, the etiological agent of scrub typhus, is an antigenically diverse organism and many serologically distinct strains have been identified. The 56 kDa protein of O. tsutsugamushi, a major protein in the outer membrane, has been thought to be responsible for this antigenic variability. A strain of O. tsutsugamushi isolated in Korea cross-reacted with both Gilliam strain-specific and Karp strain-specific monoclonal antibodies. When its 56 kDa protein gene was cloned and analyzed, its sequence showed variation especially between 1,200 and 1,250 bp, showing that this isolate is a new O. tsutsugamushi strain.
ISSN
0385-5600
URI
https://hdl.handle.net/10371/202716
DOI
https://doi.org/10.1111/j.1348-0421.1997.tb01876.x
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