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Isolation of a new Orientia tsutsugamushi serotype
Cited 11 time in
Web of Science
Cited 12 time in Scopus
- Authors
- Issue Date
- 1997-06
- Publisher
- Center for Academic Publications Japan
- Citation
- Microbiology and Immunology, Vol.41 No.6, pp.437-443
- Abstract
- Orientia tsutsugamushi, the etiological agent of scrub typhus, is an antigenically diverse organism and many serologically distinct strains have been identified. The 56 kDa protein of O. tsutsugamushi, a major protein in the outer membrane, has been thought to be responsible for this antigenic variability. A strain of O. tsutsugamushi isolated in Korea cross-reacted with both Gilliam strain-specific and Karp strain-specific monoclonal antibodies. When its 56 kDa protein gene was cloned and analyzed, its sequence showed variation especially between 1,200 and 1,250 bp, showing that this isolate is a new O. tsutsugamushi strain.
- ISSN
- 0385-5600
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