Publications

Detailed Information

Jamun fruit extract enhances growth performance, mucosal immunity, disease resistance, and immune- and antioxidant-related gene expression of Cyprinus carpio juveniles

Cited 0 time in Web of Science Cited 0 time in Scopus
Authors

Giri, Sib Sankar; Kim, Sang Guen; Jun, Jin Woo; Chi, Cheng; Saha, Subrata; Sukumaran, Venkatachalam; Park, Se Chang

Issue Date
2024-06
Publisher
Elsevier BV
Citation
Aquaculture Reports, Vol.36, p. 102123
Abstract
This study evaluated the effects of Jamun fruit extract (JFE) on the growth, immunity, and health of juvenile Cyprinus carpio (average weight: 9.08±0.47 g). Diets containing five different JFE concentrations, that is, 0 (control), 2 (JFE2), 3 (JFE3), 4 (JFE4), and 5 g Kg−1 (JFE5) were fed to five fish groups (maintained in triplicate) for eight weeks. Growth parameters were examined at 4 and 8 weeks post-feeding; whereas, immune and antioxidant-related parameters were measured at 8 weeks post-feeding. Fish were challenged with Aeromonas hydrophila at the end of the feeding trial and mortalities were recorded over 14 days post-infection. Weight gain rate (%) was significantly higher in JFE3, compared to the control. RBC and WBC counts, hemoglobin, total protein level, albumin, and phagocytic activity were significantly enhanced in JFE3 than in control; whereas, there was no significant effect on hematocrit, and blood glucose level. Skin mucosal lysozyme and peroxidase levels were significantly higher in JFE2 ̶ JFE4 than in the control. Significantly higher mucosal total immunoglobulin, alkaline phosphatase, and protein levels were recorded in JFE3. Serum MDA and AST levels were significantly lower in JFE2 ̶ JFE4 than in the control; however, the MPO level was highest in JFE3. Liver antioxidant enzymatic activities were strongly enhanced in JFE3. Further, JFE supplementation upregulated the expression of antioxidant-related genes in the liver. The mRNA expression of TNF-α and IL-1β was upregulated in the kidney and intestine in JFE3. Kaplan–Meier survival curves revealed that the probability of survival (64.69%) was highest in JFE3. Quadratic regression analysis followed by optimization showed that the optimal dietary JFE level was estimated to be 2.59 ̶ 2.74 g Kg−1 to maximize the growth performance. Therefore, JFE at appropriate doses could improve the growth, immunity, and disease resistance of C. carpio against A. hydrophila.
ISSN
2352-5134
URI
https://hdl.handle.net/10371/203979
DOI
https://doi.org/10.1016/j.aqrep.2024.102123
Files in This Item:
There are no files associated with this item.
Appears in Collections:

Related Researcher

  • College of Veterinary Medicine
  • Department of Veterinary Medicine
Research Area Bacteriophage Therapy, Veterinary Medicine, Veterinary Microbiology

Altmetrics

Item View & Download Count

  • mendeley

Items in S-Space are protected by copyright, with all rights reserved, unless otherwise indicated.

Share