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Ridge regeneration of damaged extraction sockets using rhBMP-2: an experimental study in canine
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Lee, Jung-Seok | - |
dc.contributor.author | Jung, Jae-Suk | - |
dc.contributor.author | Im, Gun-Il | - |
dc.contributor.author | Kim, Byung-Soo | - |
dc.contributor.author | Cho, Kyoo-Sung | - |
dc.contributor.author | Kim, Chang-Sung | - |
dc.date.accessioned | 2024-06-13T02:13:55Z | - |
dc.date.available | 2024-06-13T02:13:55Z | - |
dc.date.created | 2018-01-10 | - |
dc.date.created | 2018-01-10 | - |
dc.date.issued | 2015-07 | - |
dc.identifier.citation | Journal of Clinical Periodontology, Vol.42 No.7, pp.678-687 | - |
dc.identifier.issn | 0303-6979 | - |
dc.identifier.uri | https://hdl.handle.net/10371/204282 | - |
dc.description.abstract | Objectives: This study evaluated the dimensional ridge alteration in a buccal-bone-deficient extraction socket, and ridge regeneration following socket grafting accompanied by recombinant human bone morphogenetic protein 2 (rhBMP-2) or a collagen membrane covering. Material and Methods: In five beagle dogs, entire buccal bone of the extracted sockets of premolars was surgically removed and immediately grafted using one of the following graft protocols: (1) sham surgery without any grafting, and grafting with (2) deproteinized bovine bone mineral (DBBM), (3) DBBM/rhBMP-2 and (4) DBBM covered with a collagen membrane (DBBM/Membrane). Quantitative/qualitative analyses were performed radiographically/histologically after 8weeks. Results: Buccal-deficient extraction sockets healed with significant reduction in buccolingual dimension along the entire length of the socket, but all grafting techniques reduced the dimensional changes compared to the non-grafted control sites. Histologically, sites received DBBM only exhibited minimal regeneration, whereas sites grafted with DBBM/rhBMP-2 or DBBM/Membrane exhibited greater new bone formation extending the entire augmented area. Conclusions: Buccal-bone-deficiency may lead to significant volume reduction after tooth extraction along the entire length of the socket, and socket grafting accompanied by rhBMP-2 or covered with a membrane can be candidate therapies for preservation of the buccolingual dimension and successful ridge regeneration. | - |
dc.language | 영어 | - |
dc.publisher | Blackwell Publishing Inc. | - |
dc.title | Ridge regeneration of damaged extraction sockets using rhBMP-2: an experimental study in canine | - |
dc.type | Article | - |
dc.identifier.doi | 10.1111/jcpe.12414 | - |
dc.citation.journaltitle | Journal of Clinical Periodontology | - |
dc.identifier.wosid | 000358198500009 | - |
dc.identifier.scopusid | 2-s2.0-84937639211 | - |
dc.citation.endpage | 687 | - |
dc.citation.number | 7 | - |
dc.citation.startpage | 678 | - |
dc.citation.volume | 42 | - |
dc.description.isOpenAccess | N | - |
dc.contributor.affiliatedAuthor | Kim, Byung-Soo | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.subject.keywordPlus | TOOTH EXTRACTION | - |
dc.subject.keywordPlus | PRESERVATION | - |
dc.subject.keywordPlus | BONE | - |
dc.subject.keywordPlus | COLLAGEN | - |
dc.subject.keywordPlus | DOG | - |
dc.subject.keywordAuthor | alveolar ridge augmentation | - |
dc.subject.keywordAuthor | bone morphogenetic protein 2 | - |
dc.subject.keywordAuthor | guided bone regeneration | - |
dc.subject.keywordAuthor | ooth extraction | - |
dc.subject.keywordAuthor | ridge preservation | - |
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