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마우스 두개골 결손 모델에서 지방줄기세포와 BMP-2의 골 재생 효능 비교 : Comparison of osteogenic potential between adipose-derived stem cells and BMP-2 in a mouse calvarial defect model
DC Field | Value | Language |
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dc.contributor.author | Kang, Sun Woong | - |
dc.contributor.author | La, Wan-Guen | - |
dc.contributor.author | Kang, Jin-Muk | - |
dc.contributor.author | Lee, Jong-Ho | - |
dc.contributor.author | Park, Jung-Ho | - |
dc.contributor.author | Kim, Byung-Soo | - |
dc.date.accessioned | 2024-06-13T02:20:03Z | - |
dc.date.available | 2024-06-13T02:20:03Z | - |
dc.date.created | 2018-06-20 | - |
dc.date.created | 2018-06-20 | - |
dc.date.issued | 2007-09 | - |
dc.identifier.citation | TISSUE ENGINEERING AND REGENERATIVE MEDICINE, Vol.4 No.3, pp.382-387 | - |
dc.identifier.issn | 1738-2696 | - |
dc.identifier.uri | https://hdl.handle.net/10371/204381 | - |
dc.description.abstract | In vivo bone regeneration can be achieved either by transplantation of osteogenic cells differentiated from adipose-derived stem cells (ADSCs) or by delivery of exogenous bone morphogenetic protein-2 (BMP-2). In this study, we compared the osteogenic potential between ADSCs and BMP-2 in a mouse calvarial defect model. Critical-sized circular calvarial defects were made in nude mice. The mice were randomized into 4 groups (n=6 per group) that were treated with either 1) fibrin glue alone, 2) fibrin glue with BMP-2, 3) fibrin glue with undifferentiated ADSCs, or 4) fibrin glue with osteogenically differentiated ADSCs. Specimens were harvested at 8 weeks after treatment and evaluated radiographically and histologically. Differentiation of human ADSCs prior to transplantation did not affect bone regeneration. Transplantation of ADSCs was not superior to BMP-2 delivery for in vivo bone formation in a mouse calvarial defect model. | - |
dc.language | 한국어 | - |
dc.publisher | KOREAN TISSUE ENGINEERING REGENERATIVE MEDICINE SOC | - |
dc.title | 마우스 두개골 결손 모델에서 지방줄기세포와 BMP-2의 골 재생 효능 비교 | - |
dc.title.alternative | Comparison of osteogenic potential between adipose-derived stem cells and BMP-2 in a mouse calvarial defect model | - |
dc.type | Article | - |
dc.citation.journaltitle | TISSUE ENGINEERING AND REGENERATIVE MEDICINE | - |
dc.identifier.wosid | 000258567400010 | - |
dc.citation.endpage | 387 | - |
dc.citation.number | 3 | - |
dc.citation.startpage | 382 | - |
dc.citation.volume | 4 | - |
dc.identifier.kciid | ART001283745 | - |
dc.description.isOpenAccess | N | - |
dc.contributor.affiliatedAuthor | Lee, Jong-Ho | - |
dc.contributor.affiliatedAuthor | Kim, Byung-Soo | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.subject.keywordPlus | IN-VITRO | - |
dc.subject.keywordPlus | BONE | - |
dc.subject.keywordPlus | DIFFERENTIATION | - |
dc.subject.keywordPlus | REPAIR | - |
dc.subject.keywordPlus | TISSUE | - |
dc.subject.keywordPlus | FAT | - |
dc.subject.keywordAuthor | adipose-derived stein cells | - |
dc.subject.keywordAuthor | bone morphogenetic protein-2 | - |
dc.subject.keywordAuthor | tissue engineering | - |
dc.subject.keywordAuthor | fibrin glue | - |
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