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The role of transforming growth factor-beta and bone morphogenetic protein with fibrin glue in healing of bone-tendon junction injury : The role of transforming growth factor-β and bone morphogenetic protein with fibrin glue in healing of bone-tendon junction injury
DC Field | Value | Language |
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dc.contributor.author | Kim, Hak-Jun | - |
dc.contributor.author | Kang, Sun-Woong | - |
dc.contributor.author | Lim, Hong-Chul | - |
dc.contributor.author | Han, Seung-Bum | - |
dc.contributor.author | Lee, Jae-Sun | - |
dc.contributor.author | Prasad, Leela | - |
dc.contributor.author | Kim, Yoon-Jung | - |
dc.contributor.author | Kim, Byung-Soo | - |
dc.contributor.author | Park, Jung-Ho | - |
dc.date.accessioned | 2024-06-14T01:04:08Z | - |
dc.date.available | 2024-06-14T01:04:08Z | - |
dc.date.created | 2018-06-18 | - |
dc.date.issued | 2007-11 | - |
dc.identifier.citation | CONNECTIVE TISSUE RESEARCH, Vol.48 No.6, pp.309-315 | - |
dc.identifier.issn | 0300-8207 | - |
dc.identifier.uri | https://hdl.handle.net/10371/204547 | - |
dc.description.abstract | Bone-tendon junction injuries have poor healing potential. This study evaluated the role of TGF-beta and BMP-2 in a fibrin glue carrier in healing of injuries at bone-tendon junction. Seventy-two skeletally mature male rabbits were divided into 4 groups. The tendo-Achilles was surgically transected at its insertion and reattached with a pullout suture. Group 1 served as a control. In groups 2, 3, and 4, fibrin glue, a mixture of TGF-beta and fibrin glue, and a mixture of BMP-2 and fibrin glue were injected into the bone-tendon junction. The animals were sacrificed at 2, 4 and 8 weeks after surgical procedure. The addition of TGF-beta to fibrin glue did not significantly improve the biomechanical properties of repair tissue. BMP-2 in combination with fibrin glue accelerates healing in a bone-tendon injury and also improves the histological and biomechanical properties of the repair tissue so formed. | - |
dc.language | 영어 | - |
dc.publisher | TAYLOR & FRANCIS LTD | - |
dc.title | The role of transforming growth factor-beta and bone morphogenetic protein with fibrin glue in healing of bone-tendon junction injury | - |
dc.title.alternative | The role of transforming growth factor-β and bone morphogenetic protein with fibrin glue in healing of bone-tendon junction injury | - |
dc.type | Article | - |
dc.identifier.doi | 10.1080/03008200701692610 | - |
dc.citation.journaltitle | CONNECTIVE TISSUE RESEARCH | - |
dc.identifier.wosid | 000251632500005 | - |
dc.identifier.scopusid | 2-s2.0-37349001266 | - |
dc.citation.endpage | 315 | - |
dc.citation.number | 6 | - |
dc.citation.startpage | 309 | - |
dc.citation.volume | 48 | - |
dc.description.isOpenAccess | N | - |
dc.contributor.affiliatedAuthor | Kim, Byung-Soo | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.subject.keywordPlus | GENE-TRANSFER | - |
dc.subject.keywordPlus | RABBIT MODEL | - |
dc.subject.keywordPlus | TGF-BETA | - |
dc.subject.keywordPlus | IN-VITRO | - |
dc.subject.keywordPlus | LIGAMENT | - |
dc.subject.keywordPlus | REPAIR | - |
dc.subject.keywordPlus | TUNNEL | - |
dc.subject.keywordPlus | CELLS | - |
dc.subject.keywordPlus | RECONSTRUCTION | - |
dc.subject.keywordPlus | PROLIFERATION | - |
dc.subject.keywordAuthor | Achilles tendon | - |
dc.subject.keywordAuthor | fibrin glue | - |
dc.subject.keywordAuthor | bone morphogenetic protein | - |
dc.subject.keywordAuthor | bone-tendon junction | - |
dc.subject.keywordAuthor | transforming growth factor-beta | - |
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