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Chemical constituents from Ainsliaea acerifolia as potential anti-obesity agents
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Kim, Taewan | - |
dc.contributor.author | Jo, Cheorun | - |
dc.contributor.author | Kim, Hyun-Seok | - |
dc.contributor.author | Park, Youn-Moon | - |
dc.contributor.author | Wu, Yong-Xiang | - |
dc.contributor.author | Cho, Jae-Hyeon | - |
dc.contributor.author | Kim, Tae Hoon | - |
dc.date.accessioned | 2024-08-08T01:36:08Z | - |
dc.date.available | 2024-08-08T01:36:08Z | - |
dc.date.created | 2018-01-10 | - |
dc.date.created | 2018-01-10 | - |
dc.date.issued | 2016-06 | - |
dc.identifier.citation | Phytochemistry Letters, Vol.16, pp.146-151 | - |
dc.identifier.issn | 1874-3900 | - |
dc.identifier.uri | https://hdl.handle.net/10371/206939 | - |
dc.description.abstract | Bioassay-guided isolation of an ethanolic extract of the aerial parts from Ainsliaea acerifolia using pancreatic lipase inhibitory assay led to the isolation of a new guaianolide-type sesquiterpene lactone (1), a new dicaffeoylquinic acid derivative (4), as well as eight known secondary metabolites. Structures of the two new compounds were elucidated on the basis of spectroscopic methods. All isolated compounds were evaluated for their inhibitory effects against pancreatic lipase, and compound 2 exhibited significant inhibitory activity with an IC50 value of 15.3 +/- 0.7 mu M. Furthermore, compound 2 also exhibited potent inhibitory effects against 3T3-L1 adipocyte cells. (C) 2016 Published by Elsevier B.V. on behalf of Phytochemical Society of Europe. | - |
dc.language | 영어 | - |
dc.publisher | Elsevier BV | - |
dc.title | Chemical constituents from Ainsliaea acerifolia as potential anti-obesity agents | - |
dc.type | Article | - |
dc.identifier.doi | 10.1016/j.phytol.2016.04.005 | - |
dc.citation.journaltitle | Phytochemistry Letters | - |
dc.identifier.wosid | 000378027300025 | - |
dc.identifier.scopusid | 2-s2.0-84963604217 | - |
dc.citation.endpage | 151 | - |
dc.citation.startpage | 146 | - |
dc.citation.volume | 16 | - |
dc.description.isOpenAccess | N | - |
dc.contributor.affiliatedAuthor | Jo, Cheorun | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.subject.keywordPlus | CAFFEOYLQUINIC ACID-DERIVATIVES | - |
dc.subject.keywordPlus | SESQUITERPENE LACTONES | - |
dc.subject.keywordPlus | ADIPOCYTE DIFFERENTIATION | - |
dc.subject.keywordPlus | WEIGHT-REDUCTION | - |
dc.subject.keywordPlus | LIPASE | - |
dc.subject.keywordPlus | OBESITY | - |
dc.subject.keywordPlus | IDENTIFICATION | - |
dc.subject.keywordPlus | INHIBITORS | - |
dc.subject.keywordPlus | ALPHA | - |
dc.subject.keywordAuthor | Ainsliaea acerifolia | - |
dc.subject.keywordAuthor | Guaianolide-type sesquiterpene | - |
dc.subject.keywordAuthor | Pancreatic lipase | - |
dc.subject.keywordAuthor | Adipocyte differentiation | - |
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- College of Agriculture and Life Sciences
- Department of Agricultural Biotechnology
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