Publications
Detailed Information
Contrast-induced nephropathy after computed tomography in stable CKD patients with proper prophylaxis 8-year experience of outpatient prophylaxis program
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Park, Sehoon | - |
dc.contributor.author | Kim, Myoung-Hee | - |
dc.contributor.author | Kang, Eunjeong | - |
dc.contributor.author | Park, Seokwoo | - |
dc.contributor.author | Jo, Hyung Ah. | - |
dc.contributor.author | Lee, Hajeong | - |
dc.contributor.author | Kim, Sun Moon | - |
dc.contributor.author | Lee, Jung Pyo | - |
dc.contributor.author | Oh, Kook-Hwan | - |
dc.contributor.author | Joo, Kwon Wook | - |
dc.contributor.author | Kim, Yon Su | - |
dc.contributor.author | Kim, Dong Ki | - |
dc.date.accessioned | 2024-08-08T01:36:56Z | - |
dc.date.available | 2024-08-08T01:36:56Z | - |
dc.date.created | 2018-08-30 | - |
dc.date.created | 2018-08-30 | - |
dc.date.issued | 2016-05 | - |
dc.identifier.citation | Medicine, Vol.95 No.18, p. e3560 | - |
dc.identifier.issn | 0025-7974 | - |
dc.identifier.uri | https://hdl.handle.net/10371/206946 | - |
dc.description.abstract | Conflicting data have been reported on the clinical significance of contrast-induced nephropathy after CT scan (CT-CIN). In addition, the epidemiologic characteristics and clinical outcomes of CT-CIN following proper prophylactic intervention remain elusive. We examined the incidence, risk factors, and outcomes of CT-CIN in stable chronic kidney disease (CKD) patients using data collected from our outpatient CT-CIN prophylaxis program conducted between 2007 and 2014. The program recruited patients with an estimated glomerular filtration rate (eGFR) <60 mL/min/1.73m(2) using an electronic health record-based pop-up alert system and provided an identical protocol of CIN prophylaxis to all patients. A total of 1666 subjects were included in this study, and 61 of the 1666 subjects (3.7%) developed CT-CIN. Multivariate analysis showed that baseline eGFR, diabetes mellitus, and low serum albumin were significant risk factors for CT-CIN. The generalized additive model analysis revealed a nonlinear relationship between the baseline eGFR and the risk of CT-CIN. In this analysis, the risk of CT-CIN began to increase below an eGFR threshold of 36.8 mL/min/1.73m(2). To assess the outcomes of CT-CIN, patients with and without CT-CIN were compared after propensity score-based 1: 2 matching. CT-CIN did not increase the mortality rate of patients. However, patients with CT-CIN were significantly more likely to start dialysis within 6 months of follow-up, but not after those initial 6 months. CT-CIN developed in only a small number of stable CKD patients who received proper prophylactic intervention, and the risk of CT-CIN was increased in patients with more advanced CKD. Despite the low incidence, CT-CIN conferred a non-negligible risk for the initiation of dialysis in the acute period, even after prophylaxis. | - |
dc.language | 영어 | - |
dc.publisher | Lippincott Williams & Wilkins Ltd. | - |
dc.title | Contrast-induced nephropathy after computed tomography in stable CKD patients with proper prophylaxis 8-year experience of outpatient prophylaxis program | - |
dc.type | Article | - |
dc.identifier.doi | 10.1097/MD.0000000000003560 | - |
dc.citation.journaltitle | Medicine | - |
dc.identifier.wosid | 000376926000039 | - |
dc.identifier.scopusid | 2-s2.0-84969764535 | - |
dc.citation.number | 18 | - |
dc.citation.startpage | e3560 | - |
dc.citation.volume | 95 | - |
dc.description.isOpenAccess | Y | - |
dc.contributor.affiliatedAuthor | Lee, Jung Pyo | - |
dc.contributor.affiliatedAuthor | Oh, Kook-Hwan | - |
dc.contributor.affiliatedAuthor | Joo, Kwon Wook | - |
dc.contributor.affiliatedAuthor | Kim, Yon Su | - |
dc.contributor.affiliatedAuthor | Kim, Dong Ki | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.subject.keywordPlus | ACUTE KIDNEY INJURY | - |
dc.subject.keywordPlus | INDUCED NEPHROTOXICITY | - |
dc.subject.keywordPlus | MATERIAL EXPOSURE | - |
dc.subject.keywordPlus | PREVENTION | - |
dc.subject.keywordPlus | ACETYLCYSTEINE | - |
dc.subject.keywordPlus | RISK | - |
dc.subject.keywordPlus | METAANALYSIS | - |
dc.subject.keywordPlus | CORONARY | - |
dc.subject.keywordPlus | DISEASE | - |
- Appears in Collections:
- Files in This Item:
- There are no files associated with this item.
Item View & Download Count
Items in S-Space are protected by copyright, with all rights reserved, unless otherwise indicated.