Publications
Detailed Information
Association of body mass index and risk of death from pancreas cancer in Asians: findings from the Asia Cohort Consortium
Cited 22 time in
Web of Science
Cited 23 time in Scopus
- Authors
- Issue Date
- 2013-05
- Publisher
- Lippincott Williams & Wilkins Ltd.
- Citation
- European Journal of Cancer Prevention, Vol.22 No.3, pp.244-250
- Abstract
- We aimed to examine the association between BMI and the risk of death from pancreas cancer in a pooled analysis of data from the Asia Cohort Consortium. The data for this pooled analysis included 883 529 men and women from 16 cohort studies in Asian countries. Cox proportional-hazards models were used to estimate the hazard ratios and 95% confidence intervals for pancreas cancer mortality in relation to BMI. Seven predefined BMI categories (< 18.5, 18.5-19.9, 20.0-22.4, 22.5-24.9, 25.0-27.4, 27.5-29.9, >= 30) were used in the analysis, with BMI of 22.5-24.9 serving as the reference group. The multivariable analyses were adjusted for known risk factors, including age, smoking, and a history of diabetes. We found no statistically significant overall association between each BMI category and the risk of death from pancreas cancer in all Asians, and obesity was unrelated to the risk of mortality in both East Asians and South Asians. Age, smoking, and a history of diabetes did not modify the association between BMI and the risk of death from pancreas cancer. In planned subgroup analyses among East Asians, an increased risk of death from pancreas cancer among those with a BMI less than 18.5 was observed for individuals with a history of diabetes; hazard ratio = 2.01 (95% confidence interval: 1.01-4.00) (P for interaction = 0.07). The data do not support an association between BMI and the risk of death from pancreas cancer in these Asian populations. European Journal of Cancer Prevention 22:244-250 (C) 2013 Wolters Kluwer Health vertical bar Lippincott Williams & Wilkins.
- ISSN
- 0959-8278
- Files in This Item:
- There are no files associated with this item.
Item View & Download Count
Items in S-Space are protected by copyright, with all rights reserved, unless otherwise indicated.