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Radiolytic transformation of rotenone with potential anti-adipogenic activity
Cited 19 time in
Web of Science
Cited 23 time in Scopus
- Authors
- Issue Date
- 2013-02
- Publisher
- Pergamon Press Ltd.
- Citation
- Bioorganic and Medicinal Chemistry Letters, Vol.23 No.4, pp.1099-1103
- Abstract
- Radiolytic transformation of the isoflavonoid rotenone (1) with gamma-irradiation afforded two new degraded products, rotenoisins A (2) and (3). The structures of the two new rotenone derivatives were elucidated on the basis of spectroscopic methods. The new products 2 and 3 exhibited significantly enhanced inhibitory activities against pancreatic lipase and adipocyte differentiation in 3T3-L1 cells when compared to parent rotenone. (C) 2012 Elsevier Ltd. All rights reserved.
- ISSN
- 0960-894X
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- There are no files associated with this item.
Related Researcher
- College of Agriculture and Life Sciences
- Department of Agricultural Biotechnology
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