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A novel antiproliferative agent, phenylpyridineylbutenol, isolated from Streptomyces sp

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dc.contributor.authorShin, Choonshik-
dc.contributor.authorLim, Haeyoung-
dc.contributor.authorMoon, Sangik-
dc.contributor.authorKim, Seunghyun-
dc.contributor.authorYong, Yeonjoong-
dc.contributor.authorKim, Bum-Joon-
dc.contributor.authorLee, Chul-Hoon-
dc.contributor.authorLim, Yoongho-
dc.date.accessioned2010-01-18T04:08:48Z-
dc.date.available2010-01-18T04:08:48Z-
dc.date.issued2006-08-16-
dc.identifier.citationBioorg Med Chem Lett. 2006 Nov 1;16(21):5643-5. Epub 2006 Aug 14.en
dc.identifier.issn0960-894X (Print)-
dc.identifier.urihttp://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=16908144-
dc.identifier.urihttps://hdl.handle.net/10371/36284-
dc.description.abstractA novel compound showing antiproliferative effect was isolated from Streptomyces sp. Its structure was determined based on the interpretation of the NMR spectra, and its conformation was elucidated using molecular modeling and 2D NOESY. It was determined to be (E)-4-phenyl-3-(pyridine-2-yl)but-2-en-1-ol.en
dc.language.isoenen
dc.publisherElsevieren
dc.subjectAntineoplastic Agents/chemistry/pharmacologyen
dc.subjectButanols/chemistry/*pharmacologyen
dc.subjectCell Proliferation/*drug effectsen
dc.subjectHela Cellsen
dc.subjectHumansen
dc.subjectPyridines/chemistry/*pharmacologyen
dc.subjectStreptomyces-
dc.titleA novel antiproliferative agent, phenylpyridineylbutenol, isolated from Streptomyces spen
dc.typeArticleen
dc.contributor.AlternativeAuthor신춘식-
dc.contributor.AlternativeAuthor임혜영-
dc.contributor.AlternativeAuthor문상식-
dc.contributor.AlternativeAuthor김승현-
dc.contributor.AlternativeAuthor용연중-
dc.contributor.AlternativeAuthor김범준-
dc.contributor.AlternativeAuthor이철훈-
dc.contributor.AlternativeAuthor임영호-
dc.identifier.doi10.1016/j.bmcl.2006.08.015-
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