Supplementation of Potassium-diformate (Formi?), as an alternative of antibiotics, on growth performance, morphological changes of small intestine and immune responses in weaning Pig : 항생제 대체재로서 포테슘 다이포메이트의 첨가가 이유자돈의 성장능력과 소장의 형태학적인 변화 및 면역반응에 미치는 영향

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서울대학교 대학원
포테슘 다이포메이트Potassium-diformate (K-diformate)항생제Antibiotics이유자돈Weaning Pig
Thesis(master`s)--서울대학교 대학원 :농생명공학부,2005.
This experiment was conducted to investigate the effect of potassium-diformate
(K-diformate), as an alternative of antibiotics on growth performance,
morphological changes of small intestine and immune responses in weaning pig. A
total of 120 weaning pigs ([Landrace¡¿Yorkshire]¡¿Duroc, weaned at 25 d of age)
were allotted to 6 treatments by body weight and sex in a randomized complete
block (RCB) design in 5 replicates with 4 pigs per pen. Treatments were: 1) NCON
(basal diet), 2) P-CON (basal diet + 0.1% antibiotics), 3) F0.3 (basal diet
+ 0.3% Formi£¿), 4) F0.6 (basal diet + 0.6% Formi£¿), 5) F0.9 (basal diet + 0.9%
Formi£¿) and 6) F1.2 (basal diet + 1.2% Formi£¿). Diets were formulated with
con-soy basal, by 3 phase feeding, and all nutrients were met or exceeded
requirements of NRC (1998). Eighteen pigs (3 pigs per treatment) in 7.90 kg body
weight, were housed in an individual metabolic crate. After 7 days of adaptation
period, pigs were subjected to a 5-day collection period for nutrient
digestibility. A total of 36 weaning pigs were anatomized to measure
morphological change, pH and microbiota alteration in GI-tract. During 5 weeks
feeding trial, growth performance was not significantly differed by dietary
treatments, but positive control, F0.3 and F0.9 treatments showed improved
weight gain, subsequently final body weight was higher than other treatment
groups. Potassium diformate supplementation have influenced on pH of stomach
digesta, and was decreased as dietary K-diformate level increased. Also pigs fed
positive control diet, showed similarly effects on nutrient digestibility with
K-diformate groups, and tended to be higher than negative control although
statistical difference was not found. These results demonstrated that the
addition of K-diformate to the weaning diet was not differed from antibiotics
supplementation group in growth and increased nutrient digestibility.
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College of Agriculture and Life Sciences (농업생명과학대학)Dept. of Food and Animal Biotechnology (식품·동물생명공학부)Theses (Master's Degree_식품·동물생명공학부)
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