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급성 일산화탄소 중독과 고압 산소요법 간의 경과 시간이 백서의 임신 손모에 미치는 영향
The Experimental Study on the Relation between the Lag Time of the Hyperbaric Oxygenation and the Pregnancy Wastage of the Rat in Acute Carbon Monoxide Poisoning

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Authors
조수헌
Issue Date
1983-09
Publisher
서울대학교 의과대학
Citation
Seoul J Med, Vol.24 No.3, pp. 290-296
Abstract
Although carbon monoxide (CO) poisoning is the
most serious and prevalent noxious gas poisoning in
Korea, a few studies have been performed on the
effect of hyperbaric oxygenation (HBO) to reduce
the pregnancy wastage due to CO exposure during
gestational period.
Author designed this study to investigate the effect
of the time lag on the pregnancy wastage in the
management of acute CO poisoning with HBO. Albino
rats were exposed to 4,860ppm CO for 20 minutes
on the 11th day of gestation, and they were divided
into four groups according to the time interval
between the cessation of CO exposure and the commencement
of HBO(3 ATA, 20 minutes) such as 0
minute-, 30 minutes-, 60 minutes- and no HBO groups.
Following findings were observed as the experirnental
results,
1. The level of 10% carboxyhemoglobin was used
as the criterion of recovery. In the groups of the
lag time less than 30 minutes, the elimination time
to be recovered was 30~40 minutes. In the groups
of lag time more than 60 minutes, that was 70~90
minutes.
2. The pregnancy wastage of the groups whose lag
time was more than 60 minutes is higher than that
of the groups of lag time less than 30 minutes.
ISSN
0582-6802
Language
Korean
URI
https://hdl.handle.net/10371/6826
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College of Medicine/School of Medicine (의과대학/대학원)Dept. of Medicine (의학과)The Seoul Journal of MedicineThe Seoul Journal of Medicine Vol. 24 No.3 (1983)
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