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Fibronectin fragment promotes osteoblast-associated gene expression and biological activity of human osteoblast-like cell

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Authors
Ku, Young; Kim, Tae-Il; Jang, Jun-Hyeog; Chung, Chong-Pyoung
Issue Date
2003-12
Publisher
Springer Verlag
Citation
Biotechnology Letters 25:2007-2011.
Keywords
alkaline phosphataseextracellular matrixfibronectingene expressionosteoblast
Abstract
A fibronectin fragment, which spans from the ninth to tenth type III domain, showed >95% biological activity in promoting osteoblast adhesion, proliferation and differentiation level compared with those of native fibronectin (FN) molecule. This suggests that the FN type III ninth-tenth domain fragment serves a good substitute for native FN in biomimetic application for osteogenesis.
ISSN
0141-5492
Language
English
URI
https://doi.org/10.1023/B:BILE.0000004393.02839.d8

http://hdl.handle.net/10371/68590
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College of Dentistry/School of Dentistry (치과대학/치의학대학원)Dept. of Dentistry (치의학과)Journal Papers (저널논문_치의학과)
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