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Detection of Human Papillomavirus DNA in Condylomata Acuminata by In Situ Hybridization : In situ hybridization을 이용한 첨규콘딜롬 조직내 Human papillomavirus DNA의 검색

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Authors

Park, Kyoung Chan; Choi, Joo Hyun; Youn, Jai II; Lee, Yoo Shin; Song, Kye Yong

Issue Date
1990-06
Publisher
Seoul National University College of Medicine
Citation
Seoul J Med, Vol.31 No.2, pp. 137-140
Keywords
In situ hybridizationHuman papilloma virusesCondyloma acuminatum
Abstract
In situ hybridization using biotinylated HPV(Human papillomaviruses) probes
was tried in order to detect the presence of HPV DNA in 17 patients with condyloma
acuminatum. Fourteen cases responded with positive hybridization signals to HPV 6/11. The
specific signals were seen focally in the nuclei of superficial epithelial cells. None of the cases
were positive for HPV 16/18. There was no cross hybridization between HPV 6/11 and
HPV 16/18 under the stringent conditions used in these experiments. So it could be said
that HPV 6/11-related sequences were found in usual condyloma acuminatum.
ISSN
0582-6802
Language
English
URI
https://hdl.handle.net/10371/7312
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