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College of Medicine/School of Medicine (의과대학/대학원)
Dept. of Medicine (의학과)
The Seoul Journal of Medicine
The Seoul Journal of Medicine Vol. 31 No.2 (1990)
Detection of Human Papillomavirus DNA in Condylomata Acuminata by In Situ Hybridization
In situ hybridization을 이용한 첨규콘딜롬 조직내 Human papillomavirus DNA의 검색
- Authors
- Park, Kyoung Chan; Choi, Joo Hyun; Youn, Jai II; Lee, Yoo Shin; Song, Kye Yong
- Issue Date
- 1990-06
- Citation
- Seoul J Med, Vol.31 No.2, pp. 137-140
- Abstract
- In situ hybridization using biotinylated HPV(Human papillomaviruses) probes
was tried in order to detect the presence of HPV DNA in 17 patients with condyloma
acuminatum. Fourteen cases responded with positive hybridization signals to HPV 6/11. The
specific signals were seen focally in the nuclei of superficial epithelial cells. None of the cases
were positive for HPV 16/18. There was no cross hybridization between HPV 6/11 and
HPV 16/18 under the stringent conditions used in these experiments. So it could be said
that HPV 6/11-related sequences were found in usual condyloma acuminatum.
- ISSN
- 0582-6802
- Language
- English
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