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The burden and characteristics of tuberculosis/human immunodeficiency virus (TB/HIV) in South Korea: a study from a population database and a survey

Cited 16 time in Web of Science Cited 18 time in Scopus
Authors
Lee, Chang-Hoon; Hwang, Ji-young; Oh, Dae-Kyu; Kee, Mee-Kyung; An, Jung-wook; Do, Heonsook; Kim, Sung Soon; Nam, Jeong-Gu; Kim, Hwahyun; Kim, Hee-Jin; Kim, Jinhyun; Oh, Eunjung
Issue Date
2010-03-12
Publisher
BIOMED CENTRAL LTD
Citation
BMC INFECTIOUS DISEASES; Vol.10 ;66
Abstract
Background: Although, in South Korea, human immunodeficiency virus/acquired immunodeficiency syndrome (HIV/AIDS) keeps increasing and tuberculosis(TB) burden is still significant, there have been few reports on TB/HIV cases. In this study, we investigated the burden and characteristics of TB/HIV patients in South Korea, an area with intermediate burden of TB and a low prevalent area with HIV/AIDS. Methods: We identified patients with TB and cases with HIV between January 1 2001 and December 31 2005, from nationwide reporting system (TBnet and HIV/AIDS registry) through an electronic record linkage method. A questionnaire survey was also conducted and determined the rate of diagnosis of HIV among TB cases in public health units in 2005. Results: The number of cases with both HIV and TB was 137 (0.07% among 197,562 TB cases) and the newly detected TB/HIV cases per 100,000 population was increasing annually: 2001, 0.025; 2002, 0.031; 2003, 0.025; 2004, 0.071; 2005, 0.095. Males between 20 and 59 years of age accounted for 87.6% of TB/HIV patients. Compared with patients with TB alone, those with TB/HIV had a higher percentage of extrapulmonary TB (8.0% vs 19.0%; p < 0.0001). The standardized prevalence ratio (SPR) of HIV among patients with TB was 18.46 (95% CI, 15.50-21.83). SPR of HIV among male TB patients aged 20-59 and extrapulmonary TB cases was 39.64 (95% CI, 32.87-47.40) and 43.21 (95% CI, 28.22-63.31) respectively. Through a questionnaire survey of public health units, six patients (0.08%) were confirmed as having HIV among 7,871 TB patients in public health centers in 2005, which is similar to the result from the study through nationwide reporting systems. Conclusions: The prevalence rate of TB/HIV patients is still low but increasing in South Korea. Physicians should consider performing HIV tests among TB patients, especially in higher-risk groups, such as young males with extrapulmonary TB in South Korea.
ISSN
1471-2334
Language
English
URI
https://hdl.handle.net/10371/77382
DOI
https://doi.org/10.1186/1471-2334-10-66
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College of Medicine/School of Medicine (의과대학/대학원)Internal Medicine (내과학전공)Journal Papers (저널논문_내과학전공)
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