Browse

Midtrimester maternal plasma concentrations of angiopoietin 1, angiopoietin 2, and placental growth factor in pregnant women who subsequently develop preeclampsia

Cited 0 time in Web of Science Cited 0 time in Scopus
Authors
Shim, Soon-Sup; Jun, Jong Kwan; Lee, Cha Hee
Issue Date
2009-12
Publisher
MOSBY-ELSEVIER
Citation
AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY; Vol.201 6; S289-S289
Abstract
OBJECTIVE: To compare midtrimester maternal plasma concentrations
of angiopoietin 1, angiopoietin 2, and placental growth factor
between pregnant women who subsequently develop preeclampsia
and those who do not.
STUDY DESIGN: Midtrimester maternal plasma was collected and preserved
at 70°C when amniocentesis was performed. Cases included
37 samples of those who subsequently developed preeclampsia, and
matched controls were from those who did not develop preeclampsia.
Angiopoietin 1, angiopoietin 2, and placental growth factor concentrations
were measured by ELISA method, and compared with Mann-
Whitney U test. P value .05 was considered significant.
RESULTS: In pregnant women who subsequently developed preeclampsia,
midtrimester maternal plasma concentrations of angiopoietin
1 and angiopoietin 2 were significantly higher and placental
growth factor concentration was significantly lower than those who
did not develop preeclampsia (angiopoietin 1: 10610 [3074-19720] vs
7773 [862-24421] pg/mL, P .031; angiopoietin 2: 31038 [4666-
81199] vs 18445 [4199-49745] pg/mL, P .001; placental growth factor:
87.1 [14.2-774.3] vs 148.8 [57.2-425.6] pg/mL, P .001).
CONCLUSION: Midtrimester maternal plasma concentrations of angiopoietin
1, angiopoietin 2, and placental growth factor is risk factors for
the subsequent development of preeclampsia.
ISSN
0002-9378
Language
English
URI
https://hdl.handle.net/10371/77780
Files in This Item:
There are no files associated with this item.
Appears in Collections:
College of Medicine/School of Medicine (의과대학/대학원)Obstetrics & Gynecology (산부인과전공)Journal Papers (저널논문_산부인과학전공)
  • mendeley

Items in S-Space are protected by copyright, with all rights reserved, unless otherwise indicated.

Browse