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Fabrication of Pillar Shaped Electrode Arrays for Artificial Retinal Implants

Cited 18 time in Web of Science Cited 22 time in Scopus
Authors
Kim, Eui Tae; Seo, Jong-Mo; Woo, Se Joon; Zhou, Jing Ai; Chung, Hum; Kim, Sung June
Issue Date
2008-09
Publisher
Molecular Diversity Preservation International (MDPI)
Citation
Sensors 2008, 8, 5845-5856
Keywords
Polyimideretinal implantpillaroptical coherence tomographyelectrically evoked cortical potential
Abstract
Polyimide has been widely applied to neural prosthetic devices, such as the
retinal implants, due to its well-known biocompatibility and ability to be micropatterned.
However, planar films of polyimide that are typically employed show a limited ability in
reducing the distance between electrodes and targeting cell layers, which limits site
resolution for effective multi-channel stimulation. In this paper, we report a newly designed
device with a pillar structure that more effectively interfaces with the target. Electrode
arrays were successfully fabricated and safely implanted inside the rabbit eye in
suprachoroidal space. Optical Coherence Tomography (OCT) showed well-preserved pillar
structures of the electrode without damage. Bipolar stimulation was applied through paired
sites (6:1) and the neural responses were successfully recorded from several regions in the
visual cortex. Electrically evoked cortical potential by the pillar electrode array stimulation
were compared to visual evoked potential under full-field light stimulation.
ISSN
1424-8220
Language
English
URI
http://hdl.handle.net/10371/7919
DOI
https://doi.org/10.3390/s8095845
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College of Engineering/Engineering Practice School (공과대학/대학원)Dept. of Electrical and Computer Engineering (전기·정보공학부)Journal Papers (저널논문_전기·정보공학부)
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