Publications
Detailed Information
Fabrication of Pillar Shaped Electrode Arrays for Artificial Retinal Implants
Cited 19 time in
Web of Science
Cited 23 time in Scopus
- Authors
- Issue Date
- 2008-09
- Citation
- Sensors 2008, 8, 5845-5856
- Keywords
- Polyimide ; retinal implant ; pillar ; optical coherence tomography ; electrically evoked cortical potential
- Abstract
- Polyimide has been widely applied to neural prosthetic devices, such as the
retinal implants, due to its well-known biocompatibility and ability to be micropatterned.
However, planar films of polyimide that are typically employed show a limited ability in
reducing the distance between electrodes and targeting cell layers, which limits site
resolution for effective multi-channel stimulation. In this paper, we report a newly designed
device with a pillar structure that more effectively interfaces with the target. Electrode
arrays were successfully fabricated and safely implanted inside the rabbit eye in
suprachoroidal space. Optical Coherence Tomography (OCT) showed well-preserved pillar
structures of the electrode without damage. Bipolar stimulation was applied through paired
sites (6:1) and the neural responses were successfully recorded from several regions in the
visual cortex. Electrically evoked cortical potential by the pillar electrode array stimulation
were compared to visual evoked potential under full-field light stimulation.
- ISSN
- 1424-8220
- Language
- English
- Files in This Item:
Item View & Download Count
Items in S-Space are protected by copyright, with all rights reserved, unless otherwise indicated.