S-Space College of Engineering/Engineering Practice School (공과대학/대학원) Dept. of Electrical and Computer Engineering (전기·정보공학부) Journal Papers (저널논문_전기·정보공학부)
Optical Measurement of Neural Activity Using Surface Plasmon Resonance
- Kim, Shin Ae; Byun, Kyung Min; Lee, Jonghwan; Kim, Junghoon; Kim, Dong-Ghi Albert; Baac, Hyoungwon; Shuler, Michael L.; Kim, Sung June
- Issue Date
- Optical Society of America
- Opt. Lett. 33, 914 (2008)
- We demonstrate that surface plasmon resonance (SPR) is applicable to the optical detection of neural signals.
A low-noise SPR sensor was developed as a label- and artifact-free method for the extracellular recording
of neural activity. The optical responses obtained from a rat sciatic nerve were highly correlated with
simultaneously recorded electrical responses. Additional studies with stimulation intensity and lidocaine
further confirmed that the optically measured signals originated from neural activities.
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