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Optical Measurement of Neural Activity Using Surface Plasmon Resonance

Cited 41 time in Web of Science Cited 42 time in Scopus
Authors
Kim, Shin Ae; Byun, Kyung Min; Lee, Jonghwan; Kim, Junghoon; Kim, Dong-Ghi Albert; Baac, Hyoungwon; Shuler, Michael L.; Kim, Sung June
Issue Date
2008-05
Publisher
Optical Society of America
Citation
Opt. Lett. 33, 914 (2008)
Abstract
We demonstrate that surface plasmon resonance (SPR) is applicable to the optical detection of neural signals.
A low-noise SPR sensor was developed as a label- and artifact-free method for the extracellular recording
of neural activity. The optical responses obtained from a rat sciatic nerve were highly correlated with
simultaneously recorded electrical responses. Additional studies with stimulation intensity and lidocaine
further confirmed that the optically measured signals originated from neural activities.
ISSN
0146-9592
Language
English
URI
https://hdl.handle.net/10371/7922
DOI
https://doi.org/10.1364/OL.33.000914
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College of Engineering/Engineering Practice School (공과대학/대학원)Dept. of Electrical and Computer Engineering (전기·정보공학부)Journal Papers (저널논문_전기·정보공학부)
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