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A Suprachoroidal Electrical Retinal Stimulator Design for Long-Term Animal Experiments and

Cited 60 time in Web of Science Cited 66 time in Scopus
Authors
Zhou, Jing Ai; Woo, Se Joon; Park, Se Ik; Kim, Eui Tae; Seo, Jong-Mo; Chung, Hum; Kim, Sung June
Issue Date
2008-02
Publisher
Hindawi Publishing Corporation
Citation
Journal of Biomedicine and Biotechnology, vol. 2008, Article ID 547428, 2008
Abstract
This article reports on a retinal stimulation system for long-term use in animal electrical stimulation experiments. The presented
system consisted of an implantable stimulator which provided continuous electrical stimulation, and an external component which
provided preset stimulation patterns and power to the implanted stimulator via a paired radio frequency (RF) coil. A rechargeable
internal battery and a parameter memory component were introduced to the implanted retinal stimulator. As a result, the external
component was not necessary during the stimulation mode. The inductive coil pair was used to pass the parameter data and to
recharge the battery. A switch circuit was used to separate the stimulationmode fromthe battery recharging mode. The implantable
stimulator was implemented with IC chips and the electronics, except for the stimulation electrodes, were hermetically packaged
in a biocompatible metal case. A polyimide-based gold electrode array was used. Surgical implantation into rabbits was performed
to verify the functionality and safety of this newly designed system. The electrodes were implanted in the suprachoroidal space.
Evoked cortical potentials were recorded during electrical stimulation of the retina. Long-term follow-up using OCT showed no
chorioretinal abnormality after implantation of the electrodes.
ISSN
1110-7251
Language
English
URI
http://hdl.handle.net/10371/7924
DOI
https://doi.org/10.1155/2008/547428
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College of Engineering/Engineering Practice School (공과대학/대학원)Dept. of Electrical and Computer Engineering (전기·정보공학부)Journal Papers (저널논문_전기·정보공학부)
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