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Sensitivity Analysis of a Nanowire-Based Surface Plasmon Resonance Biosensor in the Presence of Surface roughness
Cited 36 time in
Web of Science
Cited 37 time in Scopus
- Authors
- Issue Date
- 2007-02
- Publisher
- Optical Society of America
- Citation
- J. Opt. Soc. Am. A 24, 522-529 (2007)
- Abstract
- We have investigated the effect of surface roughness on the sensitivity of conventional and nanowire-based
surface plasmon resonance (SPR) biosensors. The theoretical research was conducted using rigorous coupledwave
analysis with Gaussian surface profiles of gold films determined by atomic force microscopy. The results
suggest that, when surface roughness ranges near 1 nm, the sensitivity of a conventional SPR system is not
significantly affected regardless of the correlation length. For a nanowire-based SPR biosensor, however, we
have found that the sensitivity degrades substantially with decreasing correlation length. In particular, at a
correlation length smaller than 100 nm, a random rough surface may induce destructive coupling between excited
localized surface plasmons, which can lead to prominent reduction of sensitivity enhancement.
- ISSN
- 1084-7529 (print)
1520-8532 (online)
- Language
- English
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