S-Space College of Medicine/School of Medicine (의과대학/대학원) Dept. of Medicine (의학과) The Seoul Journal of Medicine The Seoul Journal of Medicine Vol. 05 No.4 (1964)
의학곤충의 살충제저항성에 관한 연구 제3편 한국모기의 살충제 감수성에 대하여
Studies on Insecticide Resistance of Medical Insects Part III: On Insecticide Susceptibility of Mosquitoes in Korea
- Issue Date
- 서울대학교 의과대학
- Seoul J Med, Vol.5 No.4, pp. 31-40
- Resistance to an insecticide was first recorded 1945,
in housefly. Since that time, ~ the number of insect
species of public health importance resist to one or
more insecticide has been increased year to year.
The first signs of weakening in effectiveness of
DDT against A. sacharoui appeared in Greece in 1951.
The development of other DDT-resistant anopelines
---nmaely, A. quadrimaculatus in the U.S.A., A.
sundaicus in Indonesia and A. stephensi in Iran,
resulted in a recrudescence of malaria transmission.
Dieldrin- resistance in A.gambiae in Noethern Nigeria
and Liberia has rendered dieldrin useless for malaria
With regard to the resistance of Culex pipiens pallens
in the Far Eest, in 1954., the 406th Medical
General Laboratory, U.S. Army reported that the
Culex PiPiens larvae collected from various localities
in Japan developed a remarkable resistance to
3/2 - 38-'
- D.S. Koo: Studies on Insecticide Resistance of Medical Insects-
DDT, lindane and malation as compared with the
normal culex colonies at the Orlando Laboratory,Fla.,
U.S.A. In 1960, Paik reported that the Seoul strain
of C. pipiens has not developed resistance to insecticides
so markedly. Quite recently, Suzuki & Mizutani
reported that C. pipiens in Tokyo seemed to have got
more and more resistant to DDT, lindane and dieldrin
with years, perhaps because of occasional application
of these insecticides.
During the mosquito season of 1964, the author
carried out this studies in order to ascertain the
present situation of susceptibility of Anepheles sinensis,
Culex pipiens pallens and Aedes vexans nipponii,
the most common nuisance or vector in Korea. The
susceptibility of larvae of A. sinensis and C. pipiens
to p,p'-DDT, r-BHC and malathion was tested in lab
oratory by the dipping method. The test for adult A.
sinensis, C. pipiens and Ae. uexans nipponii were
carried out by the Busvine-Nash method. Some of
important results so far obtained can be summarized
1. The LC-50 of A. sinensis to insecticides were
0.027 ppm in p,p'-DDT, 0.074 ppm in r-BHC and 0.065
ppm in malathion. The LC-50 of C. pipiens to insecticides
were 0.064 ppm in p,p'-DDT, 0.030 ppm in
r-BHC and 0.029 ppm in malathion.
2. The resistance of both of two species larvae
have not been arisen as compared with the results
observed in other part of the Far East received heavy
3. The LC-50 of A. sinensis to p,p' - DDT and dieldrin
were 1.33% and 0.09%. In C. pipiens, the LC-50 to
p,p'-DDT and dieldrin were 2.16%.and 0.28%. In Ae.
rexans nipponii, the LC-50 to p,p'-DDT and dieldrin
were 2.16% and 0.31%. C. pipiens showed to be most
tolerant to DDT and Ae. oexans nipponii was the
next. and A. sinensis was most susceptible to dieldrin.
4. In comparison with the data obtained in other
countries, it was observed that adult mosquitoes of
thses three species were still susceptible to DDT and