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Histopathological features of bisphosphonate-associated osteonecrosis: findings in patients treated with partial mandibulectomies
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Cho, Young-Ah | - |
dc.contributor.author | Yoon, Hye-Jung | - |
dc.contributor.author | Lee, Jae-Il | - |
dc.contributor.author | Hong, Sam-Pyo | - |
dc.contributor.author | Hong, Seong-Doo | - |
dc.creator | 홍성두 | - |
dc.date.accessioned | 2013-10-07T04:29:58Z | - |
dc.date.available | 2013-10-07T04:29:58Z | - |
dc.date.issued | 2012-12 | - |
dc.identifier.citation | Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology Vol.114 No.6, pp. 785-791 | - |
dc.identifier.issn | 2212-4403 | - |
dc.identifier.uri | https://hdl.handle.net/10371/83536 | - |
dc.description.abstract | The present study investigated the histopathologic and radiographic features of stage 3 bisphosphonate-associated osteonecrosis of the jaw (BAONJ) in patients who were treated with partial mandibulectomies. Bisphosphonates had been orally administered to 10 patients with osteoporosis and intravenously administered to 1 patient with metastatic carcinoma. On radiographic images, massive osteolysis and periosteal bone formations were conspicuous, and a thin mandibular cortical width was observed in 5 of 10 osteoporosis patients despite the previous use of bisphosphonate. Microscopically, the mandibulectomy specimens of the patients could be divided into 4 distinct layers. Although there were few differences in overall histologic features between BAONJ and chronic suppurative osteomyelitis, a notable number of osteoclasts were found detached from the bony trabeculae in BAONJ. | en |
dc.language.iso | en | en |
dc.publisher | Elsevier Inc. | en |
dc.subject | 의약학 | en |
dc.title | Histopathological features of bisphosphonate-associated osteonecrosis: findings in patients treated with partial mandibulectomies | en |
dc.type | Article | - |
dc.author.alternative | 조영아 | - |
dc.author.alternative | 윤혜정 | - |
dc.author.alternative | 이재일 | - |
dc.author.alternative | 홍삼표 | - |
dc.author.alternative | 홍성두 | - |
dc.identifier.doi | 10.1016/j.oooo.2012.08.457 | - |
dc.citation.journaltitle | Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology | - |
dc.description.srnd | OAIID:oai:osos.snu.ac.kr:snu2012-01/102/0000004825/1 | - |
dc.description.srnd | SEQ:1 | - |
dc.description.srnd | PERF_CD:SNU2012-01 | - |
dc.description.srnd | EVAL_ITEM_CD:102 | - |
dc.description.srnd | USER_ID:0000004825 | - |
dc.description.srnd | ADJUST_YN:Y | - |
dc.description.srnd | EMP_ID:A075646 | - |
dc.description.srnd | DEPT_CD:861 | - |
dc.description.srnd | CITE_RATE:1.457 | - |
dc.description.srnd | FILENAME:첨부된 내역이 없습니다. | - |
dc.description.srnd | DEPT_NM:치의학과 | - |
dc.description.srnd | EMAIL:hongsd@snu.ac.kr | - |
dc.description.srnd | SCOPUS_YN:Y | - |
dc.description.srnd | CONFIRM:Y | - |
dc.identifier.srnd | 2012-01/102/0000004825/1 | - |
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