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Unrefined and Refined Black Raspberry Seed Oils Significantly Lower Triglycerides and Moderately Affect Cholesterol Metabolism in Male Syrian Hamsters
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Ash, Mark M. | - |
dc.contributor.author | Wolford, Kate A. | - |
dc.contributor.author | Carden, Trevor J. | - |
dc.contributor.author | Hwang, Keum Taek | - |
dc.contributor.author | Carr, Timothy P. | - |
dc.creator | 황금택 | - |
dc.date.accessioned | 2013-10-23T04:33:05Z | - |
dc.date.available | 2013-10-23T04:33:05Z | - |
dc.date.issued | 2011-08-21 | - |
dc.identifier.citation | Journal of Medicinal Food Vol.14 No.9, pp. 1032-1038 | - |
dc.identifier.issn | 1096-620X (print) | - |
dc.identifier.issn | 1557-7600 (online) | - |
dc.identifier.uri | https://hdl.handle.net/10371/83753 | - |
dc.description.abstract | Unrefined and refined black raspberry seed oils (RSOs) were examined for their lipid-modulating effects in male Syrian hamsters fed high-cholesterol (0.12% g/g), high-fat (9% g/g) diets. Hamsters fed the refined and the unrefined RSO diets had equivalently lower plasma total cholesterol and high-density lipoprotein (HDL) cholesterol in comparison with the atherogenic coconut oil diet. The unrefined RSO treatment group did not differ in liver total and esterified cholesterol from the coconut oil-fed control animals, but the refined RSO resulted in significantly elevated liver total and esterified cholesterol concentrations. The unrefined RSO diets significantly lowered plasma triglycerides (46%; P = .0126) in comparison with the coconut oil diet, whereas the refined RSO only tended to lower plasma triglyceride (29%; P = .1630). Liver triglyceride concentrations were lower in the unrefined (46%; P = .0002) and refined (36%; P = .0005) RSO-fed animals than the coconut oil group, with the unrefined RSO diet eliciting a lower concentration than the soybean oil diet. Both RSOs demonstrated a null or moderate effect on cholesterol metabolism despite enrichment in linoleic acid, significantly lowering HDL cholesterol but not non-HDL cholesterol. Dramatically, both RSOs significantly reduced hypertriglyceridemia, most likely due to enrichment in a-linolenic acid. As a terrestrial source of a-linolenic acid, black RSOs, both refined and unrefined, provide a promising alternative to fish oil supplementation in management of hypertriglyceridemia, as demonstrated in hamsters fed high levels of dietary triglyceride and cholesterol. | en |
dc.language.iso | en | en |
dc.publisher | Mary Ann Liebert, Inc. | en |
dc.publisher | Korean Society of Food Science and Nutrition | - |
dc.subject | 복합학 | en |
dc.subject | atherosclerosis | - |
dc.subject | caneberry | - |
dc.subject | cardiovascular diseases | - |
dc.subject | hypercholesterolemia | - |
dc.subject | hypertriglyceridemia | - |
dc.subject | linoleic acid | - |
dc.subject | linolenic acid | - |
dc.subject | phytosterol | - |
dc.subject | polyunsaturated fatty acids | - |
dc.title | Unrefined and Refined Black Raspberry Seed Oils Significantly Lower Triglycerides and Moderately Affect Cholesterol Metabolism in Male Syrian Hamsters | en |
dc.type | Article | - |
dc.author.alternative | 황금택 | - |
dc.identifier.doi | 10.1089/jmf.2010.0181 | - |
dc.citation.journaltitle | Journal of Medicinal Food | - |
dc.description.srnd | OAIID:oai:osos.snu.ac.kr:snu2011-01/102/0000050589/1 | - |
dc.description.srnd | SEQ:1 | - |
dc.description.srnd | PERF_CD:SNU2011-01 | - |
dc.description.srnd | EVAL_ITEM_CD:102 | - |
dc.description.srnd | USER_ID:0000050589 | - |
dc.description.srnd | ADJUST_YN:Y | - |
dc.description.srnd | EMP_ID:A077289 | - |
dc.description.srnd | DEPT_CD:352 | - |
dc.description.srnd | CITE_RATE:1.408 | - |
dc.description.srnd | FILENAME:첨부된 내역이 없습니다. | - |
dc.description.srnd | DEPT_NM:식품영양학과 | - |
dc.description.srnd | EMAIL:keum@snu.ac.kr | - |
dc.description.srnd | CONFIRM:Y | - |
dc.identifier.srnd | 2011-01/102/0000050589/1 | - |
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