Publications
Detailed Information
High-throughput generation of spheroids using magnetic nanoparticles for three-dimensional cell culture
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Kim, Jeong Ah | - |
dc.contributor.author | Choi, Jong-Ho | - |
dc.contributor.author | Kim, Minsoo | - |
dc.contributor.author | Rhee, Won Jong | - |
dc.contributor.author | Son, Boram | - |
dc.contributor.author | Jung, Hyun-Kyo | - |
dc.contributor.author | Park, Tai Hyun | - |
dc.creator | 박태현 | - |
dc.date.accessioned | 2014-02-14T00:37:35Z | - |
dc.date.available | 2014-02-14T00:37:35Z | - |
dc.date.created | 2018-07-09 | - |
dc.date.issued | 2013-11 | - |
dc.identifier.citation | BIOMATERIALS, Vol.34 No.34, pp.8555-8563 | - |
dc.identifier.issn | 0142-9612 | - |
dc.identifier.uri | https://hdl.handle.net/10371/90917 | - |
dc.description.abstract | Various attempts have been made to develop three-dimensional (3-D) cell culture methods because 3-D cells mimic the structures and functional properties of real tissue compared with those of monolayer cultures. Here, we report on a highly simple and efficient 3-D spheroid generation method based on a magnetic pin-array system to concentrate magnetic nanoparticle-incorporated cells in a focal direction. This system was comprised only of external magnets and magnetically induced iron pins to generate a concentrated magnetic field for attracting cells in a focused direction. 3-D spheroid generation was achieved simply by adding magnetic nanoparticle-incorporated cells into a well and covering the plate with a magnetic lid. Cell clustering occurred rapidly within 5 min and created more compact cells with time through the focused magnetic force. This system ensured not only reproducible and size-controlled generation of spheroids but also versatile types of spheroids such as random mixed, core-shell, and fused spheroids, providing a very useful tool for various biological applications. (C) 2013 Elsevier Ltd. All rights reserved. | - |
dc.language | 영어 | - |
dc.language.iso | en | en |
dc.publisher | ELSEVIER SCI LTD | - |
dc.title | High-throughput generation of spheroids using magnetic nanoparticles for three-dimensional cell culture | - |
dc.type | Article | - |
dc.author.alternative | 김정아 | - |
dc.author.alternative | 최종호 | - |
dc.author.alternative | 김민수 | - |
dc.author.alternative | 이원종 | - |
dc.author.alternative | 손보람 | - |
dc.author.alternative | 정현교 | - |
dc.author.alternative | 박태현 | - |
dc.identifier.doi | 10.1016/j.biomaterials.2013.07.056 | - |
dc.citation.journaltitle | BIOMATERIALS | - |
dc.identifier.wosid | 000324450600002 | - |
dc.identifier.scopusid | 2-s2.0-84882815407 | - |
dc.description.srnd | OAIID:oai:osos.snu.ac.kr:snu2013-01/102/0000002410/15 | - |
dc.description.srnd | SEQ:15 | - |
dc.description.srnd | PERF_CD:SNU2013-01 | - |
dc.description.srnd | EVAL_ITEM_CD:102 | - |
dc.description.srnd | USER_ID:0000002410 | - |
dc.description.srnd | ADJUST_YN:Y | - |
dc.description.srnd | EMP_ID:A002014 | - |
dc.description.srnd | DEPT_CD:458 | - |
dc.description.srnd | CITE_RATE:7.604 | - |
dc.description.srnd | FILENAME:15. (2013.11) high-throughput generation of spheroids using magnetic.pdf | - |
dc.description.srnd | DEPT_NM:화학생물공학부 | - |
dc.description.srnd | EMAIL:thpark@snu.ac.kr | - |
dc.description.srnd | SCOPUS_YN:Y | - |
dc.description.srnd | CONFIRM:Y | - |
dc.citation.endpage | 8563 | - |
dc.citation.number | 34 | - |
dc.citation.startpage | 8555 | - |
dc.citation.volume | 34 | - |
dc.description.isOpenAccess | N | - |
dc.contributor.affiliatedAuthor | Park, Tai Hyun | - |
dc.identifier.srnd | 2013-01/102/0000002410/15 | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.subject.keywordPlus | STEM-CELLS | - |
dc.subject.keywordPlus | TISSUE | - |
dc.subject.keywordPlus | DIFFERENTIATION | - |
dc.subject.keywordPlus | 3RD-DIMENSION | - |
dc.subject.keywordPlus | MANIPULATION | - |
dc.subject.keywordPlus | LEVITATION | - |
dc.subject.keywordPlus | DIMENSION | - |
dc.subject.keywordPlus | GROWTH | - |
dc.subject.keywordPlus | MODEL | - |
dc.subject.keywordAuthor | 3-Dimensional (3-D) cell culture | - |
dc.subject.keywordAuthor | Magnetic field | - |
dc.subject.keywordAuthor | Magnetic nanoparticles | - |
dc.subject.keywordAuthor | Spheroid | - |
dc.subject.keywordAuthor | Tissue engineering | - |
- Appears in Collections:
- Files in This Item:
- There are no files associated with this item.
Item View & Download Count
Items in S-Space are protected by copyright, with all rights reserved, unless otherwise indicated.