오가피성분의 중추신경에 대한 작용

Abstract

Acanthopanax spinosus Miq. is one of Arailaceae family plants which has been known as tonics in orient. We obtained glucoside fraction from methanol extract of Acanthopanax and observe its effect on conditioned avoidance response and emotional change in rats. Acanthopanax glucoside depressed the condi tioned responses but glucoside did not affect the learning. Acanthopanax glucoside decreased the number of fecal balls during conditioned avoidance responce. It is suggested that Acanthopanax glucoside may depress the fearfulness derived from noxious stimuli or unfamiliar enviroment.