만성 실혈성 빈혈자에서 Cr51에 의한 적혈구의 반감 전생 수명 측정

Abstract

Chromated cell technique was employed in measuring the half survival time of red blood cells in four chronic posthemorrhagic anemic subjects. The half survival time was 28. 5, 31.5, 29.3 , 29.2 days , respectively. These values were not different from that of control values in two normal subjects (26. 2, 28. 2 days , respe' ctively). Discontinuation of the frequent and short in· tervaled blood donation, which caused normovolemic oligocythaemia, in the subjects studied, resulted in the decrease of replacement of red blood cells per day. There were increase in hematocrit value , hemoglobin concentration and red cell volume. The fact that normal hemopoietic stimulus such as acute blood loss could not elicite increased hemopoiesis in chronic post· hemorrhagic anemic subjects was discussed.