Publications
Detailed Information
Screening of target-specific olfactory receptor and development of olfactory biosensor for the assessment of fungal contamination in grain Screening of target-specific olfactory receptor and development of olfactory biosensor for the assessment of fungal contamination in grain
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Ahn, Jung Ho | - |
dc.contributor.author | Lim, Jong Hyun | - |
dc.contributor.author | Park, Juhun | - |
dc.contributor.author | Oh, Eun Hae | - |
dc.contributor.author | Son, Manki | - |
dc.contributor.author | Hong, Seunghun | - |
dc.contributor.author | Park, Tai Hyun | - |
dc.date.accessioned | 2016-01-28T05:26:26Z | - |
dc.date.available | 2016-01-28T05:26:26Z | - |
dc.date.created | 2018-07-09 | - |
dc.date.issued | 2015-04 | - |
dc.identifier.citation | Sensors and Actuators, B: Chemical, Vol.210, pp.9-16 | - |
dc.identifier.issn | 0925-4005 | - |
dc.identifier.uri | https://hdl.handle.net/10371/95457 | - |
dc.description.abstract | We herein report an integrated olfactory system to carbon nanotube platforms for biosensing applications. In particular, this system can be used for the real-time monitoring of fungal contamination in grain through detecting 1-octen-3-ol, which is specifically generated from contaminated grain. A specific human olfactory receptor (OR) that recognizes 1-octen-3-ol was found using a cyclic adenosine monophosphate (cAMP) response element (CRE)-reporter gene assay. Then, OR-containing nanovesicles were produced from human embryonic kidney (HEK)-293 cells. The nanovesicles, which generate olfactory signals using endogenous cellular components and over-expressed ORs, were integrated into single-walled carbon nanotubes field-effect transistors (SWNT-FETs). The nanovesicles and SWNT-FETs play roles in perceiving specific odorants, and in amplifying cellular signals, respectively. Thus, the nanovesicle-integrated device was able to detect 1-octen-3-ol with excellent sensitivity and selectivity, similar to the original olfactory system. This system can be effectively utilized for the real-time measurement of fungal contamination in grain. (C) 2014 Elsevier B.V. All rights reserved. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | Elsevier BV | - |
dc.title | Screening of target-specific olfactory receptor and development of olfactory biosensor for the assessment of fungal contamination in grain Screening of target-specific olfactory receptor and development of olfactory biosensor for the assessment of fungal contamination in grain | - |
dc.type | Article | - |
dc.contributor.AlternativeAuthor | 안종호 | - |
dc.contributor.AlternativeAuthor | 임종현 | - |
dc.contributor.AlternativeAuthor | 박주훈 | - |
dc.contributor.AlternativeAuthor | 오은해 | - |
dc.contributor.AlternativeAuthor | 손만기 | - |
dc.contributor.AlternativeAuthor | 홍승훈 | - |
dc.contributor.AlternativeAuthor | 박태현 | - |
dc.identifier.doi | 10.1016/j.snb.2014.12.060 | - |
dc.citation.journaltitle | Sensors and Actuators, B: Chemical | - |
dc.identifier.wosid | 000350000000002 | - |
dc.identifier.scopusid | 2-s2.0-84920862648 | - |
dc.description.srnd | OAIID:oai:osos.snu.ac.kr:snu2015-01/102/0000002410/5 | - |
dc.description.srnd | EMP_ID:A002014 | - |
dc.description.srnd | DEPT_CD:458 | - |
dc.description.srnd | FILENAME:2. (2015.04) screening of target-specific olfactory receptor and development of.pdf | - |
dc.description.srnd | DEPT_NM:화학생물공학부 | - |
dc.description.srnd | SCOPUS_YN:N | - |
dc.description.srnd | CONFIRM:Y | - |
dc.citation.endpage | 16 | - |
dc.citation.startpage | 9 | - |
dc.citation.volume | 210 | - |
dc.description.isOpenAccess | N | - |
dc.contributor.affiliatedAuthor | Hong, Seunghun | - |
dc.contributor.affiliatedAuthor | Park, Tai Hyun | - |
dc.identifier.srnd | 2015-01/102/0000002410/5 | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.subject.keywordPlus | SURFACE-PLASMON RESONANCE | - |
dc.subject.keywordPlus | THIN-LAYER-CHROMATOGRAPHY | - |
dc.subject.keywordPlus | BIOELECTRONIC NOSE | - |
dc.subject.keywordPlus | FUNCTIONAL EXPRESSION | - |
dc.subject.keywordPlus | ODORANT RECEPTORS | - |
dc.subject.keywordPlus | LIQUID-CHROMATOGRAPHY | - |
dc.subject.keywordPlus | SIGNAL-TRANSDUCTION | - |
dc.subject.keywordPlus | ELECTRONIC NOSE | - |
dc.subject.keywordPlus | CYCLIC-AMP | - |
dc.subject.keywordPlus | MYCOTOXINS | - |
dc.subject.keywordAuthor | Bioelectronic nose | - |
dc.subject.keywordAuthor | Nanovesicle | - |
dc.subject.keywordAuthor | Carbon nanotube | - |
dc.subject.keywordAuthor | Fungal contamination | - |
dc.subject.keywordAuthor | 1-Octen-3-ol | - |
- Appears in Collections:
- Files in This Item:
- There are no files associated with this item.
Item View & Download Count
Items in S-Space are protected by copyright, with all rights reserved, unless otherwise indicated.