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Stepwise self-assembly of a protein nanoarray from a nanoimprinted poly(ethylene glycol) hydrogel
Cited 30 time in
Web of Science
Cited 30 time in Scopus
- Authors
- Issue Date
- 2008-03
- Publisher
- Wiley-Blackwell
- Citation
- Small 2008, 4, 342
- Keywords
- arrays ; hydrogels ; nanolithography ; proteins ; self-assembly
- Abstract
- Ultraviolet nanoimprint lithography is used to fabricate nanopatterns of poly(ethylene glycol) (PEG) hydrogel on gold substrates for the construction of protein nanoarrays. A protein nanoarray with a minimum feature size of 100 nm is constructed in the nanowell of the PEG hydrogel by self-assembly with a biotinylated PEG-disulfide, streptavidin, and biotinylated antibody, sequentially (see figure), and confirmed by varying the nanowell height between each step in both solution and air.
- ISSN
- 1613-6810
- Language
- English
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